Pranam
Q1 A flat fall; spoon eating is not at all in the eastern sector in the
annals of history read so far; spoon is west; sticks maybe there; chirattai
may be theer; but not spoon. There is no difference in the food habits of
india anywhere; the ingredients may be territorial; but the preparations
are one and the same; to eat North Dahi and south Thayir components may not
be different; but Pizza is totally different.
Q2 Why D is a vitamin and not calcitriol? (ans)" Regarding the recent
article by Shaygannejad et al. [1], we are writing to express serious
concerns about the portrayal of the intervention and the authors’
interpretation and discussion of the findings. Of predominate concern is
that the authors utilized a calcitriol intervention in their study but
referred to it as “vitamin D”. The erroneous use of the term “vitamin D” is
of concern for several reasons. Firstly, vitamin D is the biologically
inactive form that can be synthesized in the skin when exposed to
ultraviolet B radiation and is found in foods. In order to produce the
active metabolite, calcitriol (or 1,25-dihydroxyvitamin D; 1,25(OH)2D),
vitamin D must be hydroxylated in two subsequent reactions by two separate
hydroxylases. The second hydroxylation step—conversion of 25-hydroxyvitamin
D [25(OH)D] to 1,25(OH)2D via 1*α*-hydroxylase—is under tight regulatory
control. By providing adequate substrate (i.e., vitamin D), circulating
25(OH)D concentrations increase and cells are able to locally produce and
use 1,25(OH)2D in a self-regulated manner without affecting circulating
levels of calcitriol. In contrast, supplying calcitriol directly produces a
systemic increase in calcitriol, thus bypassing the key regulatory steps
and increases risk of hypercalcemia. On the other hand, supplementation
with vitamin D is quite safe at levels up to 10,000 IU/d [2, 3]. Wingerchuk
et al. [4] have previously demonstrated the risk of hypercalcemia with
calcitriol treatment in patients with MS. With this sole exception [4],
none of the published vitamin D-related trials in patients with MS have
administered calcitriol; the authors failed to note this or compare the
findings of their calcitriol intervention to the only other published
calcitriol intervention in MS. The differences in the safety profile and
activity of vitamin D versus calcitriol alone are significant and
necessitate accurate nomenclature."
"Next, the authors indicate “no unusual or unexpected safety risks found
with vitamin D therapy in our study population with RRMS”; however, not
only did they administer calcitriol rather than vitamin D, but also no
characterization of the dosage nor description of the rationale for the
selected dosage was present. Furthermore, since there is neither mention of
serum calcium, urine calcium nor 1,25(OH)2D levels in response to therapy
dose, we cannot assess the effect of oral calcitriol [1,25(OH)2D]
supplementation on biochemical outcomes in these patients. Overall, the
authors’ naivety regarding metabolism of vitamin D is evidenced in that
they (i) neglected to monitor calcium or calcitriol levels when treating
with calcitriol, (ii) monitored 25(OH)D levels—which are the biomarker of
vitamin D status in the normal situation but are not relevant during
calcitriol therapy, and (iii) directly compare studies of supplementation
with vitamin D, calcitriol, and alfacalcidol (a synthetic analogue of
calcitriol) without distinguishing the various forms and their inherently
different activity. In conclusion, the work presented here “*a calcitriol
intervention in adults with MS*” cannot be directly compared with the
majority of the previous vitamin D-related MS interventions in the
literature. Barring instances of genetic mutations causing dysfunction of
the 1-alpha hydroxylase, at present, there is no rationale to support the
use of calcitriol over vitamin D. (Research authentic article). { KR I do
not illegally or out of enemity or as ignorant, write on, as few here would
presume; I also read a lot from many directions; but the moment I read, I
raise a question, IS THAT ALL or MANY FACES MORE TO IT? THESE TYPE OF SOME
ONE WRITTEN , HAD BEEN QUESTIONED ,WHILE REPRODUCING THEM, MAY BE BE IT
WOULD HAVE BEEN PRESENTED WITH A PROS AND CONS; OR STOPPED PRESS. But the
mind refuses to yield what they advise others; if carefully seen , I do not
add to everything, only a selectrive. Let there be light.
Q3 Is that a doubt at this age?.
Q5 Is there only one SUN IN THE UNIVERSE?. There are so many SUNs in the
universe; there are many black holes 4 times of the so many universities,
(known are less than 1%) ,getting created everyday and getting destroyed
everyday; srishti and pralayams are occuring every second; so destruction
of SUN is end is neither science nor the theology.
Q7 Again this can be reviewed as the answer is erroneous; atoms do not
come back again; molecular and cellular are jumbo of words without any
understanding.
Q11 again not at this age but a fable to kids. KR IRs 3322
On Wed, 2 Mar 2022 at 20:38, 'gopala krishnan' via iyer123 <
[email protected]> wrote:
> *CULTURAL QA 03-2022-02*
>
> *BEING A COMPILATION THERE MAY BE ERRORS*
>
> Q1 What is the major difference between North Indians and
> South Indians while eating food?
>
> A1 Nandakumar Lived in Bengaluru, Karnataka, India Feb 23
>
> *Most South Indian foods couldn’t be enjoyed with a spoon*. Indeed you
> can try with a spoon. But it won’t give such satisfaction as eating with
> hand. And anyway never try eating in banana leaf with a spoon :)
>
> So the main difference is most South Indians prefer to eat food by hand!
>
> *And most North Indians prefer a spoon or else try to use hand but without
> touching the curry directly by the hand*. Anyway, most of their food
> items are not watery like South. And I have seen a few battling to eat Dosa
> with a fork as well :) That’s a crime indeed :)
>
> If you have any different and interesting observations please share. My
> knowledge is based on what I observe in Bengaluru mostly!
>
> Q2 Is vitamin D the only vitamin that a person can get without
> eating any food, or is vitamin D actually not a vitamin, but a hormone or a
> steroid hormone?
>
> A2 Ken Saladin Author, Anatomy & Physiology—The Unity of Form
> and Function Sat
>
> *I treat it as a hormone and steroid derivative*; it is not in itself a
> steroid, but it’s synthesized from cholesterol. I usually use the name
> calcitriol for it, as I think *it’s misleading and unfortunate that it
> came to be called a vitamin*—just one of many common misconceptions.
>
> Q3 Can somebody steal money from my bank account in India
> simply by knowing my account number? There are several posts on Quora
> saying so, though these may not be from India. How can it happen?
>
> A3 Kanthaswamy Balasubramaniam Lawyer Sun
>
> Can somebody steal from your House if they know your Address?
>
> Sure but not just by knowing your address right?
>
> They have to be experienced enough to break into your house. They have to
> bypass your ferocious Guard Dog or Tough Lock. They have to ensure they
> dont wake up your neighbors. They have to find out where you keep your
> valuables. They have to know how to crack a safe.
>
> In Short - Maybe 0.1% of People who know your address can actually steal
> from your house right????
>
> Stealing knowing your Account number is possible only by around 0.00001%
> People who know your account number.
>
> Lets say i know your Account Number
>
> How do i know which Bank?
>
> Lets say i know your Bank and Account Number. Then i can probably find out
> which Branch easily enough and transfer money to your account.
>
> But thats the maximum i can do
>
> Why?
>
> → I dont know your Signature so i cannot sign a debit voucher
>
> → I dont have your Looks so i cannot get a debit voucher even if i can
> forge your signature
>
> → I dont have a Chequebook so i cannot issue a cheque
>
> → I dont have your username or password - so i cannot login to your online
> banking account
>
> → I dont have your Mobile Phone so cannot get the OTP for transactions
>
> → I dont have your Mobile numbers so cannot use any mobile banking sites
>
> → I dont have your ATM Card or ATM Pin - So i cannot use your ATM Card to
> draw money
>
> So only you can provide me with any of the above so that i can take money
> from your account
>
> A Signed Cheque, Your ATM Card and Pin, Your Mobile Phone Set and MPIN or
> Online Username and Password etc.
>
> Whom do you give such details to?
>
> Family, Friends, Maybe….Colleagues
>
> Do you give such info to Strangers?????
>
> *So No - NO WAY that anyone can take money just by knowing your account
> number*
>
> Q4 What does it mean when a washing machine says 7kg? Is that
> 7kg dry weight of clothes, wet clothes or 7kg wet clothes with water?
>
> A4 Gopala Krishnan , former Assistant General Manager
> 1996-2004 at Department of Telecom (1966-2004)Answered just now
>
> As I understand capacity 7kg of a washing machine meant weight of clothes
> dipped/socked in water. Normally one cannot wash more than 2 thick
> bed-sheets in a 5kg washing machine. This is my experience and
> understanding from company technicians. By experience one can understand
> the socked weight of clothes. Further a washing machine should not be
> loaded above 75% of it’s capacity.
>
> Q5 Why do scientists claim that the Sun will eventually be the
> Earth's demise?
>
> A5 Steve Baker Senior Software Engineer (2013–present)Feb 25
>
> We can calculate the mass of the sun - and the rate at which it’s
> converting hydrogen into helium. *We know that when stars similar to the
> sun run out of hydrogen, they start burning helium instead.*
>
> During that transition, the sun will get brighter and about 2,000 times
> larger. We know this because we can see other stars that have suffered
> the same fate.This huge expansion will boil the Earth’s oceans, blow away
> the atmosphere and then melt the entire planet.
>
> Although the Sun will by then have engulfed Mercury and Venus - it’s
> expansion will stop short of swallowing Earth - but the Sun’s upper
> atmosphere will extend out beyond Earth, so that will cause drag - which
> will slow the Earth down until it crashes into the Sun.
>
> Q6 Who produces lentils?
>
> A6 Ian De Pagie food blogger Feb 22
>
> *The biggest producer of lentils is Canada. Followed by India. Together
> they produce almost 60%*
>
> Whereas Indians eat their lentils, *Canadians don’t.* They export the
> whole lot. Producing on a big scale they manage to keep prices down. So low
> that other foreign producers think twice before cultivating them. Sicilian
> lentils, among the best in the world, are sold for no less than the double
> Canadian lentils cost. And although your lentil soup will be better when
> using Sicilian lentils, Canadian lentils do the trick.
>
> *Back to your question: Canadians produce lentils as a cash crop. Others
> do it out of tradition.*
>
> Q7 Shouldn’t our bodies return back to the Earth? How can that
> happen in a casket?
>
> A7 Ken Saladin A student of life Feb 25
>
> *So much of our body is recycled at the molecular to cellular level
> repeatedly during our lifetimes.* What’s left of it when we die is a
> vanishingly small fraction of the matter that comprises our bodies during
> our lifetimes. *Ninety-nine point nine nine nine umpty nine percent of
> one’s body is returned to the earth*. What little bit goes into a casket
> is trivial compared to all we’ve been between birth and death. Just another
> way of looking at it.
>
> Q8 Do you clean under your furniture from time to time?
>
> A8 Elizabeth Henderson, former English Teacher. Answered Tue
>
> *Define “from time to time” ...*
>
> I run the vacuum cleaner round the house whenever visitors are
> expected.Occasionally I feel energetic and my arthritic hands aren’t too
> painful, and then I go a bit further.Otherwise I leave the dust bunnies in
> peace.
>
> Q9 How do the railway authorities decide to stop trains at a
> particular station?
>
> A9 Prashant Tiwari Indian Railways Enthusiast Sun
>
> Stoppage of any train at particular station depends on multiple factors *like
> foot fall, station’s value* on its *route, its historical importance and
> Requests from MP of that area.*
>
> Foot fall and historical importance are two major aspects through which
> Railway decides the stoppage of any train.
>
> Exceptions are always there as Sampoorna Kranti SF Express skips Prayagraj
> Jn. which has a huge foot fall & historical importance too. This train
> skips this station bacause of its own reputation which is “ Aam logo ki
> Rajdhani”.
>
> Q10 Why are oysters so hard to open?
>
> A10 Martin Bayer Chef (1994–present)Feb 25
>
> Oysters are alive. Inside of that hard shell is a simple bivalve organism
> that is delicate and squishy. Animals like otters, bears and even bald
> eagles, (yeah, bald eagles!) eat oysters. The hard to open shell slows
> them down.All of those animals do eventually get inside and snack on the
> squishy oyster flesh, but the shell keeps them from eating all of them.
> The shells protect the species from being gobbled into extinction.
>
> Q11 I usually see geckos in my house and I am very
> scared. Are they harmful to human life? Do they bite?
>
> A11 Claire Jordan Degree in biology and folklore; programmer,
> shop owner, secretary on newspaper Tue
>
> No, they’re harmless. The worst they can do is startle you if they lose
> their grip on the ceiling and fall on you. They’re cute, shy and hoover up
> bugs some of which really might harm you. As others have said, *they
> won’t bite unless you grab them and if they do, it’ll just be a mild nip
> like a small puppy’s.*
>
> Q12 Do you carefully choose your faucet for a kitchen sink?
>
> A12 John Sergent, likes ketchup Answered Sun
>
> I do, yes. I want one that will last as long as possible, of the type I
> prefer to use, in a style and finish that suits its surroundings.The first
> is to put off having to do more plumbing work; the others are because, if
> I’m going to be using and looking at it for many years, I might as well get
> it just right.
>
> *All the above QA are from Quora website on 02-03- 2022. **Quora
> answers need not be 100% correct answers .*
>
> *Compiled **and posted by R. Gopala krishnan on 02-03-2022*
>
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