In a message dated 9/30/2007 12:14:36 P.M. Eastern Daylight Time,  
[EMAIL PROTECTED] writes:

More  questions then:

Would the effects of carbs be anything like the  supposed effects of 
tryptophan? And does eating a normal sized portion of  turkey or drinking a 
glass of 
warm milk really do anything measurable within a  human being?

Annette


Annette Kujawski Taylor,  Ph.D.
Professor of Psychology
University of San Diego
5998 Alcala  Park
San Diego, CA  92110
619-260-4006
[EMAIL PROTECTED]



Hi Annette -
 
I am guessing that Judith Wurtman and her husband, Robert, would say  yes. A 
few early studies are abstracted below. She has published several popular  
books on the subject (such as, Serotonin Solution). It seems that her  work has 
become ever more popularized:  
_http://www.dietdetective.com/content/blogcategory/61/177/_ 
(http://www.dietdetective.com/content/blogcategory/61/177/) 
 
Hope this helps.  =)
 
_Adv Exp Med  Biol._ (javascript:AL_get(this, 'jour', 'Adv Exp Med Biol.');)  
1996;398:35-41. _Links_ (javascript:PopUpMenu2_Set(Menu9045545);)   
Brain Serotonin, Carbohydrate-craving, obesity and  depression.
_Wurtman  RJ_ 
(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term="Wurtman%20RJ"[Author]&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPa
nel.Pubmed_RVAbstractPlus) , _Wurtman  JJ_ 
(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term="Wurtman%20JJ"[Author]&itool=EntrezSystem2.PE
ntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus) .
Department of Brain and Cognitive Sciences, Clinical  Research Center 
Massachussetts Institute of Technology, Cambridge 02139,  USA. 
PMID: 9045545 [PubMed - indexed for MEDLINE]
_Obstet  Gynecol._ (javascript:AL_get(this, 'jour', 'Obstet Gynecol.');)  
1995 Oct;86(4 Pt 1):520-8. 
(http://www.ncbi.nlm.nih.gov/entrez/utils/fref.fcgi?PrId=3051&itool=AbstractPlus-def&uid=7675373&db=pubmed&url=http://www.greenjourna
l.org/cgi/pmidlookup?view=long&pmid=7675373)  _Links_ 
(javascript:PopUpMenu2_Set(Menu7675373);)   
The effect of a carbohydrate-rich beverage on mood, appetite,  and cognitive 
function in women with premenstrual syndrome.
_Sayegh  R_ 
(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term="Sayegh%20R"[Author]&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.
Pubmed_RVAbstractPlus) , _Schiff  I_ 
(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term="Schiff%20I"[Author]&itool=EntrezSystem2.PEntrez.Pu
bmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus) , _Wurtman  J_ 
(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term="Wurtman%20J"[Author]&ito
ol=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus) , 
_Spiers  P_ 
(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term="Spiers%20P"[Author]&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.P
ubmed_RVAbstractPlus) , _McDermott  J_ 
(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term="McDermott%20J"[Author]&itool=EntrezSystem2.PEntr
ez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus) , _Wurtman  R_ 
(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term="Wurtman%20R"[Author
]&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbst
ractPlus) .
Division of Reproductive Endocrinology and Infertility,  Vincent Memorial 
Obstetrics and Gynecology Service, Massachusetts General  Hospital, Harvard 
Medical School, Boston, USA. 
OBJECTIVE: To test the efficacy of a specially-formulated,  carbohydrate-rich 
beverage (one known to increase the serum ratio of tryptophan  to other large 
neutral amino acids) on the mood, cognitive, and appetitive  disturbances of 
premenstrual syndrome (PMS). METHODS: Twenty-four women with  confirmed PMS 
were enrolled in a double-blind, crossover study to test the  efficacy of the 
specially-formulated beverage compared with two other isocaloric  products on 
PMS symptoms. The study was conducted over three menstrual cycles  preceded by 
a 
1-month placebo run-in. Patients were tested at home or work using  an 
interactive computer-telephone system. Standardized measurements of mood,  
cognitive 
performance, and food cravings were made before and 30, 90, and 180  minutes 
after consumption of active and placebo beverages during the late luteal  
phase of the menstrual cycle. RESULTS: The experimental carbohydrate  
intervention 
significantly decreased self-reported depression, anger, confusion,  and 
carbohydrate craving 90-180 minutes after intake. Memory word recognition  was 
also improved significantly compared with scores obtained during the placebo  
run-in month (P < .05). The isocaloric placebo interventions had no  
significant 
effect on any of these measures. CONCLUSION: The results suggest  that the 
psychological and appetitive symptoms of PMS can be relieved after  consuming a 
specially-formulated, carbohydrate-rich beverage known to increase  serum 
tryptophan levels. 
_Drugs._ (javascript:AL_get(this, 'jour', 'Drugs.');)  1990;39  Suppl 
3:49-52. _Links_ (javascript:PopUpMenu2_Set(Menu2197075);)  
Carbohydrate craving. Relationship between carbohydrate intake  and disorders 
of mood.
_Wurtman  JJ_ 
(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term="Wurtman%20JJ"[Author]&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPa
nel.Pubmed_RVAbstractPlus) .
Massachusetts Institute of Technology, Cambridge. 
Common to repetitive episodes of weight gain or failures to  succeed on 
weight loss regimens is the excessive consumption of  carbohydrate-rich foods 
in 
association with dysphoria. The brain  neurotransmitter, serotonin, seems to be 
involved in the abnormal regulation of  mood and food intake that underlies 
diet failures or weight gain in individuals  who suffer from carbohydrate 
craving obesity (CCO), premenstrual syndrome (PMS)  and seasonal affective 
disorder 
(SAD). All 3 syndromes are characterized by  episodic bouts of increased 
carbohydrate consumption and depressed mood. Studies  with dietary treatment or 
drugs that enhance serotoninergic neurotransmission  have found that increased 
serotonin neurotransmission is associated with  normalised food intake and 
mood. 
These results suggest that periodic  intervention with dietary or drug 
treatment that increases serotonin  availability may help sustain weight or 
assist 
in weight loss. 

****************************************************** 
Sandra M.  Nagel, Ph.D. 
Associate Professor, Psychology 
Saginaw Valley State  University 
166 Brown Hall 
7400 Bay Road 
University Center, MI 48710  

http://www.svsu.edu/~smnagel/research/ 

Office: (989) 964-4635  
Fax: (989) 790-7656 
E-Mail: [EMAIL PROTECTED]  

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