Source: www.pmsescape.com/files/PMS_EffectofCarbohydrate.pdf
The Effect of a Carbohydrate-Rich Beverage on Mood, Appetite, and Cognitive Function in Women with Premenstrual Syndrome RAJA SAYEGH, MD, ISAAC SCHIFF, MD, JUDITH WURTMAN, MD, PAUL SPIERS, PhD, JANINE McDERMOTT, BA, AND RICHARD WURTMAN, MD Three dietary interventions were tested. The experimental beverage, designated A, contained a mixture of simple and complex carbohydrates previously shown to raise the serum trytophan to large neutral amino acid ratio significantly above fasting levels and hypothesized to be the most likely dietary intervention to alter premenstrual symptoms. Two other beverages, designated B and C, were also tested; these were similar in appearance and identical in calorie content to beverage A but contained mixtures of protein and carbohydrate (B) or carbohydrates (C) that left the serum trytophan to large neutral amino acid ratio unchanged. In an earlier pilot test on volunteers, consumption of drink A, which contained 47.5 g of a mixture of dextrose and maltodextrin, caused a 29% increase in the serum trytophan to large neutral amino acid ratio at 90 minutes (mean [standard error of the mean] T0 = 0168 [0.016], T90 = 0.217 [0.025], p<.05), and this increase was sustained 180 minutes after intake. Control drink B consisted of 15g of casein and 32.5g of dextrose; its consumption caused a slight and insignificant decrease in the plasma trptophan to large neutral amino acid ratio (T0 = 0.888 [0.007], T90 =0.086 [0.004]). Control drink C contained 47.5g of a mixture of galactose and dextrose; this increased the serum trytophan to large neutral amino acid ratio by less than 4% (T0 = 0.107 [0.004], T90 = 0.112 [0.004]). Based on these data, we assumed that using the three drinks in a randomized, blinded study would distinguish the effects of consuming calories per se (drink B) or carbohydrates per se (drink C) from the effects of consuming nutrients that presumably enhance serotonin-mediated neurotransmission (drink A). Drink B was also used as the placebo run-in product during the first month of testing. On Sep 30, 2007, at 7:27 PM, <[EMAIL PROTECTED]> <[EMAIL PROTECTED]> wrote: > WHOA! Where do I get this special carbo-enhanced beverage??? > > I want some! >> >> Ray Rogoway [EMAIL PROTECTED] ---
