The UWF IRB pretty much follows the guidelines of OHRP at the one-year
anniversary of an IRB approval.  Not all of the questions posed below are
requested because they are not relevant to the UWF context (no multi-center
trials).  If data collection will persist beyond the 1-year anniversary,
researchers are required to submit a second (renewal) application for
another year of data collection.

As far as I can determine, these regulations only apply to the collection of
data.  Other aspects of research (data analysis, manuscript preparation,
submission to conferences, publication) do not involve interaction with
human participants and cannot impose risks to them.  As such, I don't think
they are subject to these regulations.

One exception might be for data files that contain confidential information
that might be linked to specific individuals.  In these cases, I would
expect that the full IRB review would have included stipulations about how
these data are secured, how confidentiality is protected, both in
maintaining the data file and in dissemination of results.  Such an IRB
approval might include reporting regular reporting requirements that these
stipulations are adhered to that might extend beyond the period of data
collection.  Annette doesn't indicate that her project is in (or not in)
this category.

Information from the Office of Human Research Protection on purposes and
procedures for continuing review (the 1 year summary reports):

http://www.hhs.gov/ohrp/humansubjects/guidance/contrev0107.htm#WHAT_OCCURS_IF_THERE_IS_A_LAPSE_IN_CONTI

In conducting continuing review of research not eligible for expedited
review, all IRB members should at least receive and review a protocol
summary and a status report on the progress of the research that includes:

�         the number of subjects accrued;

�         a summary of any unanticipated problems and available information
regarding adverse events (in many cases, such a summary could be a simple
brief statement that there have been no unanticipated problems and that
adverse events have occurred at the expected frequency and level of severity
as documented in the research protocol, the informed consent document, and
any investigator brochure);

�         a summary of any withdrawal of subjects from the research since
the last IRB review;

�         a summary of any complaints about the research since the last IRB
review;

�         a summary of any recent literature that may be relevant to the
research and any amendments or modifications to the research since the last
IRB review;

�         any relevant multi-center trial reports;

�         any other relevant information, especially information about risks
associated with the research; and

�         a copy of the current informed consent document and any newly
proposed consent document.

Later on this site (cases where the 1 year review does not occur and IRB
approval lapses):



*WHAT OCCURS IF THERE IS A LAPSE IN CONTINUING REVIEW?***

The IRB and investigators must plan ahead to meet required continuing review
dates. If an investigator has failed to provide continuing review
information to the IRB or the IRB has not reviewed and approved a research
study by the continuing review date specified by the IRB, the research must
stop, unless the IRB finds that it is in the best interests of individual
subjects to continue participating in the research interventions or
interactions. Enrollment of new subjects cannot occur after the expiration
of IRB approval.

When continuing review of a research protocol does not occur prior to the
end of the approval period specified by the IRB, IRB approval expires
automatically. Such expiration of IRB approval does not need to be reported
to OHRP as a suspension of IRB approval under HHS regulations.




Claudia J. Stanny, Ph.D.
Director
Center for University Teaching, Learning, and Assessment
Associate Professor
School of Psychological and Behavioral Sciences
University of West Florida
11000 University Parkway
Pensacola, FL  32514 – 5751

Phone:   (850) 857-6355 or  473-7435

[email protected]

CUTLA Web Site: http://uwf.edu/cutla/
Personal Web Pages: http://uwf.edu/cstanny/website/index.htm

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