On Friday, July 12, 2013 1:48:06 AM UTC+1, Christoph Junghans wrote:
>
> 2013/7/11  <[email protected] <javascript:>>: 
> > Dear Users, 
> > 
> > I am running IBI - My system  involves 90 beads, protein chain. Each 
> > iteration is 5 ns and I am running 50 of them - at the begining. What I 
> see 
> > is that the first RDF has 100 times higher maximum than the target RDF. 
> In 
> > the second iteration it has 50 time higher maximum... in the third one 
> it 
> > has 5000 higher. 
> Have a look at the trajectory with vmd, it might be that your protein 
> forms a globule and never opens up again. 
>

Yes, this is true! It forms a globule and stack in this conformation. That 
means the interactions are is too attractive... Would you suggest something?
I was thinking about using fully repulsive between acidic residues and 
basic residues? And maybe exclude 1-4 interactions or divide them by 2?

Steven

 

>
> > Is that normal to have such fluctuations? Or maybe I have wrong values 
> of 
> > kbT in my settings which is 
> > 
> >  <!-- 300*0.00831451 gromacs units --> 
> >     <kBT>2.49435</kBT> 
> The order seems ok. And VOTCA will cross-check it with the value in 
> your mdp file. 
> > 
> > Please, advise. 
> > 
> > Steven 
> > 
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> > 
>
>
>
> -- 
> Christoph Junghans 
> Web: http://www.compphys.de 
>

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