2013/8/22 Chandan Choudhury <[email protected]>:
> Dear votca users,
>
> I am stucked in some basic work flow of CG.
>
> I am using 1.3-dev version of votca with gmx 4.6.3.
>
> I have generated the distributions of bonds of the beads from the mapped
> atomistic simulation. The beads are in the following sequence
> A1-B1-C1-B2-D1-B3-C2-B4-D2-B5-C3-E1. Bonds are defined in the cg mapping
> file as:
>     <bond> <name>AB.bond</name>  <beads>
>         A1 B1
>      </beads> </bond>
>     <bond>  <name>BC.bond</name> <beads>
>         B1 C1
>         C1 B2
>         B3 C2
>         C2 B4
>         B5 C3
>       </beads> </bond>
>     <bond> <name>BD.bond</name> <beads>
>         B2 D1
>         D1 B3
>         B4 D2
>         D2 B5
>       </beads> </bond>
>  <bond> <name>CE.bond</name>  <beads>
>         C3 E1
>       </beads> </bond>
>
> First, I have computed all the bonded distributions and then normalized it
> and inverted to obtain the respective potentials. I have also calculated the
> force (-dV/dr). This potential and force severs as an input for the
> step_001. I have attached the distribution and potential (for AB bead).
> After the completion of step_001, I obtain the distributions and potentials
> (*.new). I see that in step_001 the AB.bond samples different space (fig
> attached). As the sampling regions are not overlapping, so the potential
> update would be wrong. The same behaviour is also observed for the BD.bond.
> While BC and CE bonds shows resonable distributions.  Can someone guide me
> regarding this?  The potential for the AB.bond dips around 0.34. So, the
> same should also be reflected in the AB.bond distribution. Hope I am making
> a correct statement. What would be the possible reasons that forces the AB
> bond to sample around 0.37 instead for 0.34 nm? Any insight would be very
> helpful.

It looks like something might be wrong in your coarse-grained topology.

It could also be problematic to iterate on all interactions at the
same time. Play with do_potential in your settings file.
You could also try to coarse grain the bonded interactions first from
a single molecule in vacuum.
Or replace the bonded interactions by a very stiff springs and iterate
on the non-bonded interactions first and then do IBI on the springs
again.

Btw, the target distributions for csg_inverse for bonded interactions
should be calculated with csg_stat and hence don't include the 1/r^2
and 1/sin normalization.

Christoph


>
> Chandan
>
> --
> Chandan kumar Choudhury
> NCL, Pune
> INDIA
>
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-- 
Christoph Junghans
Web: http://www.compphys.de

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