On Thu, Aug 22, 2013 at 8:46 PM, Christoph Junghans <[email protected]>wrote:

> 2013/8/22 Chandan Choudhury <[email protected]>:
> > Dear votca users,
> >
> > I am stucked in some basic work flow of CG.
> >
> > I am using 1.3-dev version of votca with gmx 4.6.3.
> >
> > I have generated the distributions of bonds of the beads from the mapped
> > atomistic simulation. The beads are in the following sequence
> > A1-B1-C1-B2-D1-B3-C2-B4-D2-B5-C3-E1. Bonds are defined in the cg mapping
> > file as:
> >     <bond> <name>AB.bond</name>  <beads>
> >         A1 B1
> >      </beads> </bond>
> >     <bond>  <name>BC.bond</name> <beads>
> >         B1 C1
> >         C1 B2
> >         B3 C2
> >         C2 B4
> >         B5 C3
> >       </beads> </bond>
> >     <bond> <name>BD.bond</name> <beads>
> >         B2 D1
> >         D1 B3
> >         B4 D2
> >         D2 B5
> >       </beads> </bond>
> >  <bond> <name>CE.bond</name>  <beads>
> >         C3 E1
> >       </beads> </bond>
> >
> > First, I have computed all the bonded distributions and then normalized
> it
> > and inverted to obtain the respective potentials. I have also calculated
> the
> > force (-dV/dr). This potential and force severs as an input for the
> > step_001. I have attached the distribution and potential (for AB bead).
> > After the completion of step_001, I obtain the distributions and
> potentials
> > (*.new). I see that in step_001 the AB.bond samples different space (fig
> > attached). As the sampling regions are not overlapping, so the potential
> > update would be wrong. The same behaviour is also observed for the
> BD.bond.
> > While BC and CE bonds shows resonable distributions.  Can someone guide
> me
> > regarding this?  The potential for the AB.bond dips around 0.34. So, the
> > same should also be reflected in the AB.bond distribution. Hope I am
> making
> > a correct statement. What would be the possible reasons that forces the
> AB
> > bond to sample around 0.37 instead for 0.34 nm? Any insight would be very
> > helpful.
>
> It looks like something might be wrong in your coarse-grained topology.


I will have a re-look at the topology.

>
> It could also be problematic to iterate on all interactions at the
> same time. Play with do_potential in your settings file.
> You could also try to coarse grain the bonded interactions first from
> a single molecule in vacuum.
> Or replace the bonded interactions by a very stiff springs and iterate
> on the non-bonded interactions first and then do IBI on the springs
> again.
>
> Btw, the target distributions for csg_inverse for bonded interactions
> should be calculated with csg_stat and hence don't include the 1/r^2
> and 1/sin normalization.
>

Does it imply that csg_stat includes the normalization. As the
distributions overlap with the csg_boltzmann output, then it should also
include the normalization.

Chandan

>
> Christoph
>
>
> >
> > Chandan
> >
> > --
> > Chandan kumar Choudhury
> > NCL, Pune
> > INDIA
> >
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>
>
> --
> Christoph Junghans
> Web: http://www.compphys.de
>
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