Dear Wolfram,


For the past several years, Rigaku has been installing only HPC (Hybrid Photon 
Counting) X-ray area detector -based diffractometer systems: in conjunction 
with microfocus rotating anode, microfocus sealed-tube and other X-ray sources. 
 (Most recently, we have been deploying the Rigaku HyPix-6000HE HPC detector.)  
The advantages of the HPC technology over any of the phosphor-based detector 
types (CCD, CMOS and CPAD, etc…) are notable: most particularly the discrete 
each-and-every single photon counting capability, extremely high dynamic range, 
small pixel size and the single pixel point function and very rapid read-out.  
With these advantages, significantly higher resolution data can be achieved, - 
and more speedily, compared to the other detector types.  (We have a number of 
established ‘application note’ examples.)  In order to prove the advantages for 
your purposes, the best might be to collect data from a range of your own 
crystal samples.  – There is an open invitation for any seriously interested 
groups to collect data from their crystals in our applications labs.  Please 
contact your local good Rigaku salesperson.

Many Thanks, Yours sincerely,

Marcus Winter
Rigaku.


From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of wtempel
Sent: Tuesday, January 15, 2019 6:20 PM
To: CCP4BB@JISCMAIL.AC.UK
Subject: [ccp4bb] hybrid photon counter in the home lab


Hi,
I would value your opinions in this equipment-related question.
Allé et al have compared detector types with a molybdemon source for a small 
molecule application<https://dx.doi.org/10.1088/0031-8949/91/6/063001>. Are 
there similar published comparisons for protein crystallography? What benefits 
can I expect from replacing a CCD detector with a hybrid photon counter at an 
energy of 8 keV and in the absence of the flux that a modern synchrotron 
provides?

Thank you in advance.
Wolfram Tempel

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