Dear Wolfram, the principles of data integration do not differ much between small molecule and macromolecular data (XDS, DIALS, HKL2000, mosflm, and SAINT can be used for either), hence the advantages reported for chemical crystallography should apply likewise for macromolecular crystals.
In addition to what is listed for small molecule, the problem of overlapping reflections due to large unit cell axis might slighlty improve with hybrid pixel detectors, when the point spread is less than for CCD et al. Best, Tim On Tue, Jan 15, 2019 at 01:20:06PM -0500, wtempel wrote: > Hi, > I would value your opinions in this equipment-related question. > Allé et al have compared detector types with a molybdemon source for a > small molecule application > <https://dx.doi.org/10.1088/0031-8949/91/6/063001>. Are there similar > published comparisons for protein crystallography? What benefits can I > expect from replacing a CCD detector with a hybrid photon counter at an > energy of 8 keV and in the absence of the flux that a modern synchrotron > provides? > > Thank you in advance. > Wolfram Tempel > > ######################################################################## > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 -- -- Tim Gruene GPG Key ID = A46BEE1A ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
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