[ccp4bb] Postdoctoral Positions in Structural Biology – Maier Lab, Biozentrum, Basel, Switzerland
The Maier Lab is looking to recruit postdoctoral scientists to study giant multienzymes, regulatory complexes and metabolic regulation. We employ a combination of structural biology techniques, in particular cryo-EM, X-ray crystallography and XL-MS at state-of-the-art level to resolve the architecture of large protein assemblies. Additionally, we aim to visualize dynamics of multienzyme factories and transient regulatory interactions in eukaryotic cells. For an overview of recent research in our team, cf. Science 351, 48-52 (2016), Nature 531, 533-537(2016); Nat Chem Biol 14, 474-479 (2018), Curr Opin Struct Biol 49, 177-189 (2018); Nature 558, 470-474 (2018). For more information, follow @MaierLab on Twitter or visit www.biozentrum.unibas.ch/maier. Our group is embedded in the focal area “Structural Biology & Biophysics”, which offers a stimulating environment for interdisciplinary research. We collaborate intensely with teams in the areas of cellular signaling and infection biology. Excellent in-house facilities for electron microscopy, proteomics, imaging, biophysics, and large-scale computing support research and training. We are looking for enthusiastic scientists who share our dedication to solving challenging problems in biology. Postdoc candidates should have obtained their PhD recently or expect to complete their PhD soon and are expected to have demonstrated their scientific excellence by at least one strong published or upcoming first author paper. Ideal candidates are trained in state-of-the-art structural biology of large assemblies using cryo-EM or X-ray crystallography or have specific prior experience in mTOR signaling or polyketide synthase biology. Experience in eukaryotic protein production, multi-scale modelling, super-resolution microscopy or single-molecule experiments is a plus. The Biozentrum of the University of Basel is one of the leading institutes worldwide for molecular and biomedical basic research and teaching. It is home to more than 30 research groups with scientists from over 40 countries. Research at the Biozentrum focuses on the areas of Cell Growth & Development, Infection Biology, Neurobiology, Structural Biology & Biophysics and Computational & Systems Biology. With its more than 500 employees, the Biozentrum is the largest department at the University of Basel’s Faculty of Science. The Biozentrum is dedicated to excellence in research and education and provides outstanding training and career development support for Postdocs. Basel is an international city with people from 150 nations. Located on the border where three countries meet - Switzerland-Germany-France -, it is Europe’s most important life sciences hub. Basel provides a high standard of living and a rich and varied cultural atmosphere. Please visit www.biozentrum.unibas.ch/maier for more information and a link to the online application portal. Informal inquiries via e-mail to timm.ma...@unibas.ch are welcome. To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1
[ccp4bb] PhD fellowships, Biozentrum Basel, Switzerland
The international PhD program of the Biozentrum, University of Basel, Switzerland, is open for applications until June, 20th. We encourage highly motivated students looking for an opportunity to carry out excellent structural biology research to apply now to the Biozentrum PhD program. The Focal Area Structural Biology & Biophysics at Biozentrum provides a collaborative environment and state-of-the-art facilities for cryo electron microscopy, X-ray crystallography, NMR spectroscopy, and nanobiology. It includes the research teams of Jan Pieter Abrahams, Stephan Grzesiek, Sebastian Hiller, Roderick Lim, Timm Maier, Tilman Schirmer, Henning Stahlberg and Camilo Perez. Key research topics are membrane proteins, large macromolecular assemblies, signalling, host-pathogen interactions, neurodegeneration, chaperones, cellular mechanics and methods development. All teams are supported by core facilities for biophysical techniques, proteomics, advanced imaging, electron microscopy and quantitative genomics. Recent research highlights include Nature, doi: 10.1038/nature2234 (2017); Nature 531,598-603 (2016); Science 351, 48-52 (2016); Nature 531, 533-537(2016); Nature 530:237-41 (2016); Cell 160, 952-962 (2015); Nature 523:236-9 (2015). For more information about groups and facilities see http://www.biozentrum.unibas.ch<http://www.biozentrum.unibas.ch/>; for specific questions feel free to contact me informally (timm.ma...@unibas.ch)<mailto:timm.ma...@unibas.ch)>. Successful candidates in this competitive program will have the opportunity to do two lab rotations before selecting a host lab at the Biozentrum for their PhD. They are generously supported by a personal fellowship (starting annual salary approx. 47.000CHF, plus an extra allowance for study-related expenses). All PhD students at the Biozentrum are mentored by PhD advisory committees and benefit from an excellent postgraduate teaching program, including specialized courses, lectures and seminar series in structural biology. A PhD association organizes retreats, career development lectures and seminars as well as soft skills courses and social activities. The Biozentrum of the University of Basel is one of the leading institutes worldwide for molecular biology research and teaching. It is home to more than 30 research groups with scientists from over 40 countries. Research at the Biozentrum focuses on the areas of Growth & Development, Infection Biology, Neurobiology, Structural Biology & Biophysics and Computational & Systems Biology. With its more than 500 employees, the Biozentrum is the largest department at the University of Basel’s Faculty of Science. Basel is an international city with inhabitants from 150 nations. Located on the border where three countries meet – Switzerland, Germany & France -, it is one of Europe’s most important life sciences hubs. Basel provides a high standard of living and a rich and varied cultural atmosphere. The application procedure includes requests for letters of reference, so start your application as soon as possible. For further information on the fellowship and online application, please visit: http://www.biozentrum.unibas.ch/excellence
[ccp4bb] PhD and Postdoc Positions in Structural Biology of Large Macromolecular Assemblies, Basel (CH)
Postdoctoral and PhD student positions are available in the research group of Timm Maier at the Biozentrum (www.biozentrum.unibas.ch/maier), University of Basel, Switzerland, to study giant multienzymes, large regulatory complexes and membrane protein assemblies. We employ a combination of structural biology techniques, including X-ray crystallography, electron microscopy, XL-MS and SAXS at state-of-the-art level to resolve the architecture of large protein assemblies. For recent examples cf. Science 351, 48-52 (2016), Nature 531, 533-537(2016), Cell 160, 952-962 (2015). Additionally, we aim to visualize dynamics of multienzyme factories and transient regulatory interactions in eukaryotic protein complexes. Our group is embedded in the focal area “Structural Biology & Biophysics” of the Biozentrum, which offers a stimulating interdisciplinary environment. We collaborate intensely with researchers in the areas of cellular signaling and infection biology. Our team is supported by excellent in-house core facilities for electron microscopy, proteomics, imaging and biophysics; dedicated large scale computing resources are available. We are looking for enthusiastic scientists who share our dedication to solving challenging problems in biology. Postdoc candidates should have obtained their PhD within the last 4 years or expect to complete their PhD soon. Ideal candidates are trained at state-of-the-art level in structural biology of large assemblies or membrane proteins using cryo-electron microscopy or X-ray crystallography; experience in eukaryotic protein production or multi-scale modelling is a plus. Postdoc candidates are expected to have demonstrated their scientific excellence by at least one strong published or upcoming first author paper. PhD candidates should have recently obtained or be about to obtain a master’s degree in biological sciences including hands-on lab work in molecular or structural biology and should be highly motivated to pursue science. Salaries start at 47040CHF/year for PhD students. The Biozentrum is dedicated to excellence in research and education and provides outstanding support and training for PhD students and Postdocs (www.biozentrum.unibas.ch/education). Basel is an international center for biomedical research, with major academic institutions and research departments of leading life science companies. Situated in Switzerland on the borders to France and Germany along the river Rhine, Basel offers a high quality of living and is home to a large expat community. Please note that until June 20th prospective PhD students interested in joining the Biozentrum could apply for a prestigious Biozentrum fellowship with additional benefits (www.biozentrum.unibas.ch/education/phd/fellowship-program). Please send your application as a single pdf document including CV, publication record and a concise outline of prior research experience together with contact details of up to three references to timm.ma...@unibas.ch. Informal inquiries via e-mail are welcome.
[ccp4bb] PhD fellowships, Biozentrum Basel, Switzerland
The international PhD program of the Biozentrum, University of Basel, Switzerland, is open for applications until June, 30th. Successful candidates in this competitive program will have a chance to do two lab rotations of two month each before selecting a host lab at the Biozentrum for their PhD. They are generously supported by a personal fellowship (currently 42000/45000/48000CHF in the 1/2/3 year, plus an extra allowance for study-related expenses, such as meetings or laptops). All PhD students at Biozentrum are mentored by a PhD advisory committee and benefit from an excellent postgraduate teaching program, including specialized lecture and seminar series in structural biology. A PhD club organizes PhD retreats as well as lectures and seminars. With around 550 staff members from more than 30 countries in five major research areas (growth and development, structural biology biophysics, neurobiology, infection biology as well as computational systems biology) Biozentrum offers an interdisciplinary atmosphere for cutting-edge research. The Focal Area Structural Biology Biophysics at Biozentrum provides a highly collaborative environment and state-of-the-art facilities for X-ray crystallography, NMR spectroscopy, electron microscopy and nanobiology. We are supported by core facilities for biophysical techniques, proteomics, advanced imaging, electron microscopy and quantitative genomics. For more information about groups and facilities see http://www.biozentrum.unibas.ch; for specific questions on the Focal Area Structural Biology Biophysics, feel free to contact me informally (timm.ma...@unibas.chmailto:timm.ma...@unibas.ch). The application procedure includes requests for letters of reference, so start your application in time. For all further information on the fellowship and online application, please visit: http://www.biozentrum.unibas.ch/excellence
[ccp4bb] Research IT Specialist in Structural Biology Biophysics, Biozentrum Basel
The Biozentrum of the University of Basel, Switzerland, invites applications for a Research IT Specialist in Structural Biology Biophysics to (i) maintain and develop scientific software and workflows in Structural Biology and Biophysics, (ii) provide training and support in programming and scripting to researchers. The position will be embedded within the Research IT team of the Biozentrum. We are looking for an enthusiastic person with technical expertise as well as communication skills. The ideal candidate is a PhD level scientist or software engineer with excellent knowledge in C and Python programming. Practical experience in scientific computing in Linux/Mac environments is required. Preferentially, the candidate has proven his/her expertise by scientific publications or by the development of software tools in the area of Structural Biology. A solid knowledge of biophysical methods, as well as physics and mathematics is an advantage. The candidate enjoys contributing to excellent science by developing novel software tools and supporting researchers in programming and scripting. The Biozentrum offers an outstanding scientific environment and a competitive salary, while Basel provides a high standard of living and a superb cultural atmosphere. Applications including CV, list of publications, examples of software development, a short summary of past experience and names and contact details for two references have to be transmitted in electronic form to hr-biozentrum-at-unibas.ch (Keyword: Research IT specialist). This position is open until filled; we aim for a starting date in early 2013. For informal enquiries please contact M. Podvinec (Research IT, michael.podvinec-at-unibas.ch) or T. Maier (Structural Biology, timm.maier-at-unibas.ch). The University of Basel is an equal opportunity employer and encourages applications from female candidates.
[ccp4bb] Leader of Biophysics Facility at the Biozentrum Basel
The Biozentrum of the University of Basel, an internationally renowned Life Sciences research institute, invites applications for the Leader of its new Biophysics Facility. We are looking for an enthusiastic person that combines technical expertise with communication skills. The ideal candidate is a PhD level scientist with practical experience and excellent theoretical knowledge in biophysical methods for the characterization of biomacromolecules and their interactions, including optical spectroscopy (fluorescence, circular dichroism), microcalorimetry, analytical ultracentrifugation and surface plasmon resonance. He/she enjoys providing excellent user training and support for measurements and data evaluation, maintains and develops an assembly of state-of-the art instruments, contributes to practical and theoretical training for students and promotes scientific collaboration in the Biozentrum. The Biozentrum offers an outstanding scientific environment and a competitive salary, while Basel provides a high standard of living and a superb cultural atmosphere. Applications including CV, list of publications and a short summary of past experience, have to be transmitted in electronic form to zs-biozent...@unibas.ch. This position is open until filled; we aim for a starting date in 2012. For informal enquiries please contact Prof. S. Grzesiek (stephan.grzesiek-at-unibas.ch, phone: +41 (0) 61 267 21 00). The University of Basel is an equal opportunity employer and encourages applications from female candidates.
[ccp4bb] Postdoc and PhD student positions, Biozentrum Basel
Postdoc and PhD student positions, Biozentrum Basel, Maier Lab Our new lab at the Biozentrum is part of the core program Structural Biology Biophysics, which gathers excellence in molecular and nanoscience research including structural studies by electron microscopy, biological NMR and X-ray crystallography. We are striving to better understand eukaryotic lipid metabolism and its regulation through structural and functional studies on large multifunctional enzymes and membrane proteins (cf. Science, 321, 1315; Nature, 459, 726; Q. Rev. Biophys., 43, 373). Our approach builds on X-ray crystallography as a key method to obtain insights at atomic resolution in combination with strategies for the stabilization, labeling and trapping of macromolecules, aided by biophysical characterization of macromolecular interactions and functional analysis. We are looking for enthusiastic scientists, who share our dedication to solve challenging problems in biology, to join our lab at Postdoc or PhD student level. PhD candidates are expected to have a master¹s degree in biological sciences and practical experience in molecular biology or protein chemistry. Postdoc candidates should have recently obtained their PhD (or obtain it soon) with practical experience in structural studies and the production of difficult protein targets in eukaryotic expression systems and are expected to have demonstrated their scientific excellence by at least one significant publication as first author. Both positions are available immediately. Basel is an international center for biomedical research, with major academic institutions and research departments of leading life science companies. Situated in Switzerland on the borders to France and Germany along the river Rhine, Basel offers a high quality of living. The Biozentrum is an internationally renowned institute for life science research. With over 400 employees from 30 countries, it is the largest natural science department of the University of Basel. If you are interested in joining our team please send a short C.V. including publication record and a concise outline of prior research experience together with addresses of up to three references to timm.ma...@unibas.ch. Informal enquiries via e-mail are welcome.
