Re: [ccp4bb] Micro/Macro crystal seeding experience

I want to second the recommendation to try microseed matrix screening. I recently had a case of a protein that did not yield any crystals after trying more than 500 conditions. Of those 500, one single condition gave to me what appeared to be crystalline material, but not distinct single

Re: [ccp4bb] Micro/Macro crystal seeding experience

Hi Rafael, have you considered crystal dehydration? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317743/ It’s not easy to implement, but high solvent content could be a reason why your crystals don’t diffract beyond 4A. Did you manage to

[ccp4bb] Position available: Scientist time-resolved crystallography

Dear all, We have an open 2-year's position for a scientist to develop time-resolved activities at the new MicroMAX beamline at the MAX IV Laboratory (https://www.maxiv.lu.se/). _Closing date for applications is Sunday January 17th._ For more information and to apply see:

[ccp4bb] postdoc cryoEM image processing

Dear colleagues, We are looking to expand our team with a postdoc to develop novel cryo-EM image processing algorithms in RELION. In particular, we are planning to use modern machine-learning approaches to tackle the problem of 3D reconstruction in the presence of continuous flexibility. This

[ccp4bb] ARISE Postdoctoral Opportunities at EMBL

The new EMBL fellowship programme, ARISE (Career Accelerator for Research Infrastructure Scientists), is open for applications! ARISE aims to offer fellowships to experienced professionals with a background in science, technology, engineering, or mathematics (STEM) who wish to advance