Harry Chesley wrote:
On 12/3/2008 8:11 AM, Richard Loosemore wrote:
 Am I right in thinking that what these people:


http://www.newscientist.com/article/mg20026845.000-memories-may-be-stored-on-your-dna.html

 are saying is that memories can be stored as changes in the DNA
 inside neurons?

 If so, that would upset a few apple carts.

Yes, but it obviously needs a lot more confirmation first. :-)

 Would it mean that memories (including cultural adaptations) could be
 passed from mother to child?

No. As far as I understand it, they are proposing changes to the DNA in the neural cells only, so it wouldn't be passed on. And I would expect that the changes are specific to the neural structure of the subject, so even if you moved the changes to DNA in another subject, it wouldn't "work."

You're right, of course.

But if this holds up, it would not be quite so crazy to imagine a mechanism that uses junk DNA signalling to get the end caps of the genital DNA to reflect the changes.

I admit, though, this is stretching it a bit ;-).

As for the changes not working in another subject: yes, it would probably be the case that specific memories are encoded in an individual-specific way. But what about more general factors? What if there were some primitive types of musical understanding, say, that were common across individuals, for example? Like, a set of very primitive concepts having to do with links between sounds and finger movements? If such general factors could be passed across, a person could inherit above average musical ability because their parents had been active musicians all their lives.

All this is fun to think about, but I confess I am mostly playing devil's advocate here.

 Implication for neuroscientists proposing to build a WBE (whole brain
 emulation):  the resolution you need may now have to include all the
 DNA in every neuron.  Any bets on when they will have the resolution
 to do that?

No bets here. But they are proposing that elements are added onto the DNA, not that changes are made in arbitrary locations within the DNA, so it's not /quite/ as bad as you suggest

It would be pretty embarrassing for people gearing up for scans with a limiting resolution at about the size of one neuron, though. IIRC that was the rough order of magnitude assumed in the proposal I reviewed here recently.



Richard Loosemore





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