> Affy recommended to use Nexus software.  To generate CNV plots, I used the 
> probe level output from Nexus.

That (generating plots) is not the point; though I am all for nice CNV plots 
(ahem, arraymap.org <http://arraymap.org/>), these have no use for data 
mining/meta-analyses etc.

I had Affymetrix representatives in my office showing me plots of our Oncoscan 
data, w/o any idea how to extract probe/segment specific values. And, while 
conversing with many colleagues, nobody knows, either.

So, for us: We're having cancer profiling raw data from a series of rare 
diseases, which is rotting since we have no way of extracting genome mapped raw 
intensities / segmentation calls etc. And we're running a resource with >50000 
cancer CNA profiles/datasets - but none of them Oncoscan (damned be thy name).

Michael.


> -keith
> 
> On Mon, Jul 10, 2017 at 6:21 AM, Francesca Scellato 
> <francesca.scell...@gmail.com <mailto:francesca.scell...@gmail.com>> wrote:
> Hi! 
> I found online this discussion because I'm looking for the CDF file for 
> Oncoscan CNV array.
> I'm new to R and data analysis but everything that I've found so far to 
> analyze CEL files requires that CDF file.
> 
> Have you managed to find a solution during these past years?
> 
> Thank you in advance.
> 
> Il giorno sabato 14 novembre 2015 00:15:03 UTC+1, Henrik Bengtsson ha scritto:
> Ok, so that complicates how one would look at the pre-processing and 
> how to normalize the signals, e.g. one should probably normalize probe 
> signals of the two CEL files separately and only merge them after this 
> step. 
> 
> A small first step would be to see if you can create a spatial image 
> of the CEL files, e.g. 
> 
> library("aroma.affymetrix") 
> df <- AffymetrixCelFile("rawData/FusionSDK_Test3/Test3/Test3-1-121502.CEL") 
> print(df) 
> 
> ## Display in R 
> img <- getImage(df) 
> display(img) 
> 
> ## Generate a PNG and view it 
> png <- writeImage(df) 
> browseURL(png) 
> 
> /Henrik 
> 
> 
> On Thu, Nov 12, 2015 at 5:05 PM, Keith C <keith...@gmail.com <>> wrote: 
> > the CEL files are generated from two separate chips and hybs. 
> > 
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