Hi,

I am first time ACT user and I am looking for answer for trivial questions,
but I could not find them in the mailing list archives. I performed
comparisons between Brucella genomes and they have been already successfully
completed!!!. But, I have a doubt about the comparisons with B. melitensis
16M files. When I performed the comparison between B. melitensis files (EMBL
or GenBank) vs B. suis or B. abortus files, it is displayed B. melitensis
genome "flipped" respect B. suis or B. abortus (e.g: dnaA is the first gen
annotated in B.suis & B. abortus genomes, but BMEI1943, homologous in B.
melitensis, is 2Mb downstream). Therefore, when the comparison is running,
the following message is displayed:
"note: hits from http://www.webact.org:80
/webact/generate?CGISESSID=40d714e7d9f9ef3b89f0b47a51c50f2e&rm=mode 4&SAVE=
blast_outl.gz have been flipp..."
I do not know if the screen (almost all blue between genomes and a double
triangle like an genomic inversion) displayed can be change by flipping the
B. melitensis sequence before running the comparison (if you know, please
let me know!!). Is it possible to perform a comparison changing the genome
orientation of B. melitensis?

Thanks,

Marcos Mancilla
Ph.D. student


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