The problem is now being fixed, http://base.thep.lu.se/ticket/1077. 
Unfortunately this problem affects all versions of BASE2 and everyone 
are recommended to upgrade to the future 2.7.2 (or later).

The problem is localized and 2.7.2 will be released later today or at 
latest tomorrow. More details on the issue will follow in the 
announcement of the new release.


Cheers,

Jari


Bob MacCallum wrote:
> Has anyone had problems with the Lowess analysis plugin?
> 
> To me it looks like it is overcorrecting.  Where a M/A plot
> is largely below the zero line before normalisation, it ends
> up largely above it afterwards.
> 
> I'm using default values (including 0 for block group size).
> Default values were always fine in BASE1.
> 
> You can look for yourself with the guest login at
> http://fungen.vectorbase.org/base2
> 
> Experiment "Male vs. female (Koutsos et al., 2007)" is a good
> small example.
> 
> I don't see a recent ticket on this (I have not upgraded in
> a few months).
> 
> cheers,
> Bob.
> 
> 

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