I am writing a package that will extend the GenomicInteractions class. I am a
statistician, so I may not know best practices when it comes to extending
existing classes (eg. should I make a new slot or simply add a column to the
`elementMetadata`? Are there existing functions that already do what I am
attempting?).
I am not familiar with Bioc-Devel decorum, so if asking this here is
inappropriate, kindly let me know.
About my project:
In the first step, I am hoping to implement a HiC binning function on HiC data
contained in a GenomicInteractions set. I aim to:
- Reorder the anchor pairs (I will explain in more detail to anyone
that wants to help)
- Collapse the regions to the desires bin width
- Sum the counts within each bin
- Update the anchors to agree with the new/updated regions
This will set the stage for the new class that I hope to create for HiC domain
calling, but I need to achieve the above tasks first.
All the best to everyone!
— Luke Klein
PhD Student
Department of Statistics
University of California, Riverside
lklei...@ucr.edu
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