Hi Eshita,

You don't need to create an average topo of your subjects, because your data is 
on the 164k fs_LR standard mesh, so the open topology files in the link I 
provided below is all you will need to define the neighbor relationships 
between the vertices.

You do need to make a decision or two, though:  The caret_command 
-metric-anova-one-way feature is a valid test, but it requires a 
cluster-forming threshold (e.g., whatever f-stat corresponds to p=.01 or 
p=.025/hem).  It can make a big difference which cluster-forming threshold you 
use, as is described here:

http://www.jneurosci.org/content/suppl/2010/02/12/30.6.2268.DC1/Supplemental_Material.pdf
page 6 and supplementary material figure 7

Instead, we now use Threshold-Free Cluster Enhancement (TFCE), which 
essentially integrates over the whole range f-stats:

http://brainvis.wustl.edu/wiki/index.php/Caret:Documentation:Statistics:TFCE_Implementation

Smith SM, Nichols TE., "Threshold-free cluster enhancement: addressing problems 
of smoothing, threshold dependence and localisation in cluster inference." 
Neuroimage. 2009 Jan 1;44(1):83-98. PMID: 18501637 
http://www.ncbi.nlm.nih.gov/pubmed/18501637

Using TFCE requires downloading caret_stats and the java runtime engine (JRE) 
that has been shown to work well with it.  (Some JREs hang or get bogged down.)

These features aren't documented in tutorials, but at least two others have 
managed to get it to work.

If you're fine with the caret_command feature, you should be good to go.

Donna


On Nov 19, 2013, at 12:26 PM, Eshita Shah <[email protected]> wrote:

> Hi Donna, 
> 
> The above script was helpful, thanks. My main concern now is to run the ANOVA 
> test (using caret_command -metric-anova-one-way). You stated earlier that I 
> don't need to worry about the open topo file, but to input into ANOVA should 
> I be creating an average topo file of all my subjects? 
> 
> Please let me know. Thank you for your patience and help. 
> 
> Eshita 
> 
> 
> On Fri, Nov 15, 2013 at 3:50 PM, Donna Dierker <[email protected]> 
> wrote:
> Scroll down eshita
> 
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> Date: Fri, 15 Nov 2013 15:15:15 -0600
> From: Donna Dierker <[email protected]>
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> 
> What you're doing seems reasonable.  If this is all you're trying to do, 
> you don't need to worry about the medial wall borders, because the open 
> topo file will exclude the medial wall vertices.
> 
> The preborder.sh script only works with the PALS 74k mesh.  This one 
> might be more helpful:
> 
> http://brainvis.wustl.edu/pub/donna/FREESURFER/SCRIPTS/2013_11/gen_depth.sh
> login pub
> password download
> 
> Replace the subject directories named like SAIS* with your own list.
> 
> 
> On 11/15/2013 02:28 PM, Eshita Shah wrote:
> > Hi Donna,
> >
> > Thank you, that clears up a lot. Just to clarify, my main purpose is 
> > to use Caret to generate sulcal depth maps for each subject and run 
> > statistical analysis (such as ANOVA) to compare the results of two 
> > groups. I have completed importing all my data to the fs_LR standard 
> > mesh, and now I have to generate sulcal depth maps and run analyses. 
> > To do this, I am planning on running the "generate depth" function 
> > from PALS-B12/preborder.sh. Will this generate the appropriate input 
> > parameters for running the one-way ANOVA test through caret_command?
> >
> > Here is a list of what's needed:
> >
> >  METRIC STATISTICS ONE-WAY ANOVA
> >      caret_command -metric-statistics-anova-one-way
> >          <fiducial-coord-file>
> >          <open-topo-file>
> >          <distortion-metric-shape-file>
> >          <distortion-column-number>
> >          <output-file-names-prefix>
> >          ...
> >          <metric-file-names>
> >
> > After the import of the data into fs_LR mesh, I have multiple coord 
> > files, shape files, and closed topo files. I do not have specific 
> > paint or border files. So I am not exactly sure how to exclude the 
> > paint files that label the medial wall from my analysis, like you 
> > stated previously. I found a command in postborder.sh that converts 
> > the closed topo file into an open topo file using the roi file that's 
> > generated for the medial wall. Any guidance on doing that would be 
> > appreciated.
> >
> > Please let me know if I'm going on the right track to generate the 
> > sulcal depth maps and run my analyses.
> >
> > Thank you,
> > Eshita
> >
> >
> > On Nov 15, 2013, at 10:07 AM, Donna Dierker <[email protected]  
> > <mailto:[email protected]>> wrote:
> >
> > >Hi Eshita,
> > >
> > >topi = topology, and I hate auto-correct
> > >You mean the surface_shape/metric files -- not the topology, right?
> > >
> > >When all your data is on a standard mesh, as Caret requires to do group
> > >analysis (except for summary stats that are not vertex-wise, e.g., 
> > >gyrification
> > >index), then typically the stats tests use a single mean midthickness and 
> > >open
> > >topology for computing the areas that are used for the TFCE/cluster
> > >distributions.
> > >
> > >You typically don't need to generate an open topo file for each subject on 
> > >the
> > >standard mesh.  You have a single paint/label file that labels the medial 
> > >wall
> > >vertices, so you can exclude them from your analysis.  Or in this case, you
> > >have an open topology file that will accomplish the same thing.  If 
> > >they're all
> > >on standard mesh, then your standard open topi file should look reasonable 
> > >with
> > >all your standard mesh midthickness surfaces.
> > >
> > >An example of a time when you would need an open topi is when you want the
> > >gyrification index computed on the native mesh.  Then you can use a 
> > >strategy
> > >like thePALS_B12.LR/postborder.sh  <http://PALS_B12.LR/postborder.sh>  
> > >(http://brainmap.wustl.edu/pub/donna/FREESURFER/SCRIPTS/2011_10/PALS_B12.LR/postborder.sh
> > > ; login pub, password download) uses in the freesurfer to PALS pipeline, 
> > > which
> > >essentially writes a border around the standard mesh medial wall; 
> > >"unprojects"
> > >the border on the standard mesh midthickness; and then projects it on the
> > >native mid thickness.  When you do that, you need to project to/from the
> > >spherical or ellipsoid, so that your medial wall border points don't get 
> > >hosed.
> > >
> > >You can use your own study-specific mean midthickness, but then you should
> > >compute your own mean distortion metric to go with it.  Besides being a 
> > >bit of
> > >a hassle, it strikes me that your results are slightly less comparable to
> > >others computed on the fs_LR standard mesh that used the more standard 
> > >Conte69
> > >mean mid thickness/distortion.  I don't use study-specific files for this
> > >purpose, unless the populations are so different (e.g., baby vs adult) 
> > >that you
> > >can't use the adult.
> > >
> > >Visualization is another story.  I almost always show the study-specific 
> > >mean
> > >midthickness for each group in morphometry studies.
> > >
> > >Donna
> >
> >
> >
> >
> > On Thu, Nov 14, 2013 at 1:38 PM, Eshita Shah <[email protected] 
> > <mailto:[email protected]>> wrote:
> >
> >    Hi Donna,
> >
> >
> >
> >    Thank you for your help. From what I understand, the topology files from 
> > each subject have to be compiled (using caret_command -metric-composite) 
> > into one, and that file is then entered into the ANOVA test. My question 
> > however, is regarding the generation of the open topo files for each 
> > subject. I have used freesurfer_to_fs_LR pipeline, and I'm wondering if the 
> > topo files generated (there is only one for each subject) are indeed the 
> > open topo file, because looking at the script for freesurfer_to_fs_LR it 
> > looks like it is the closed topo file. Any advice on how to obtain an open 
> > topo file?
> >
> >
> >    Also, to clarify, the first parameter in the ANOVA test is a fiducial 
> > coord file. I have used caret_command -surface-average to generate an 
> > average fiducial file for each hemisphere. Is this correct?
> >
> >
> >    Please let me know.
> >
> >
> >
> >
> >    Thanks,
> >
> >    Eshita
> >
> >    On Wed, Nov 13, 2013 at 10:50 PM. Donna Dierker wrote:
> >
> >    >Hi Eshita,
> >
> >    >
> >    >I always use the open topology for this purpose (i.e., excludes only 
> > medial
> >    >wall vertices).  The files here will be helpful:
> >

> >    >login pub
> >    >password download
> >    >
> >    >You can get them all in this zip file:
> >    >
> >    
> > >http://brainmap.wustl.edu/pub/donna/FREESURFER/SCRIPTS/2013_11/TFCE_164k.zip
> >    >
> >    >Just to explain what is going on, the areas in the TFCE/cluster 
> > computations
> >    >are computed on the Conte69 mean mid thickness, with the open topo file
> >    >(excluding medial wall).  The distortion maps pump up the areal value 
> > where
> >    >substantial smoothing occurs as a result of averaging individuals' 
> > coordinate
> >    >files (e.g., high 3D variability).  The intent is to make the areas 
> > more like
> >    >an individual's area would be in that region.  For folks not attuned to 
> > what
> >    >you are doing, this is during group analysis.
> >
> >    >
> >    >Cheers,
> >    >
> >    >Donna
> >
> >    >
> >    >On Tue, Nov 12, 2013 at 1:18 PM, Eshita Shah <[email protected]
> >    <mailto:[email protected]>> wrote:
> >
> >        Hello,
> >
> >        Thanks for your input. I successfully was able to use
> >        freesurfer_to_fs_LR Pipeline to import my FreeSurfer files
> >        into caret, however when I try running ANOVA, it asks for
> >        certain files that have not been generated by the pipeline.
> >        Specifically, how do I generate the
> >        "distortion-metric-shape-file" that is being asked for?
> >        Lastly, is the .topo file that is generated via the pipeline
> >        the open topo file or closed? Previously I was able generate
> >        the closed topo file, so I'm not sure if the
> >        freesurfer_to_fs_LR pipeline does the same. The parameter
> >        required for the ANOVA analysis is the open topo file.
> >
> >        Thank you,
> >        Eshita Shah
> >
> >
> >        On Thu, Nov 7, 2013 at 4:12 PM, Rouhollah Abdollahi
> >        <[email protected] <mailto:[email protected]>> wrote:
> >
> >            Hi
> >            Actually the code import the original data from freesurfer
> >            to caret then automatically you will have different node
> >            number for different subjects and hemispheres. To have the
> >            same mesh you can use Freesurfer_to_fs_LR Pipeline which
> >            is available in the caret website. It imports all the data
> >            to the same mesh which here is fs_LR mesh.
> >            Hope it helps
> >            Best
> >            Rouhi
> >
> >            On Nov 8, 2013 12:06 AM, "Eshita Shah" <[email protected]
> >            <mailto:[email protected]>> wrote:
> >
> >                Hello,
> >
> >                I have just recently started using Caret, and I am
> >                running the freesurfer2caret.sh script in order to
> >                import my FreeSurfer files into Caret as well as
> >                generate sulcal depth for all subjects. I tried doing
> >                a One-Way ANOVA test, but I've realized that the
> >                number of nodes in the metric/surface_shape files for
> >                the two subjects are different. How is it possible
> >                that the same script is creating files with different
> >                node numbers? Also, within each subject, sometimes the
> >                node numbers for the left and right hemisphere are
> >                different as well. How can I resolve this issue so I
> >                can successfully run ANOVA on my subjects?
> >
> >                Any help would be appreciated.
> >
> >                Thank you,
> >                Eshita Shah
> >
> >                _______________________________________________
> >                caret-users mailing list
> >                [email protected]
> >                <mailto:[email protected]>
> >                http://brainvis.wustl.edu/mailman/listinfo/caret-users
> >
> >
> >            _______________________________________________
> >            caret-users mailing list
> >            [email protected]
> >            <mailto:[email protected]>
> >            http://brainvis.wustl.edu/mailman/listinfo/caret-users
> >
> >
> >
> >
> >
> > -- 
> > Eshita Shah
> > University of California, Los Angeles | 2014
> > B.S. Neuroscience
> > [email protected] <mailto:[email protected]>
> >
> >
> >
> >
> > _______________________________________________
> > caret-users mailing list
> > [email protected]
> > http://brainvis.wustl.edu/mailman/listinfo/caret-users
> 
> 
> --------------060202070608050109090303
> Content-Type: text/html; charset=ISO-8859-1
> Content-Transfer-Encoding: 7bit
> 
> <html>
>   <head>
>     <meta content="text/html; charset=ISO-8859-1"
>       http-equiv="Content-Type">
>   </head>
>   <body bgcolor="#FFFFFF" text="#000000">
>     What you're doing seems reasonable.&nbsp; If this is all you're trying to
>     do, you don't need to worry about the medial wall borders, because
>     the open topo file will exclude the medial wall vertices.<br>
>     <br>
>     The preborder.sh script only works with the PALS 74k mesh.&nbsp; This one
>     might be more helpful:<br>
>     <br>
> <a class="moz-txt-link-freetext" 
> href="http://brainvis.wustl.edu/pub/donna/FREESURFER/SCRIPTS/2013_11/gen_depth.sh";>http://brainvis.wustl.edu/pub/donna/FREESURFER/SCRIPTS/2013_11/gen_depth.sh</a><br>
>     login pub<br>
>     password download<br>
>     <br>
>     Replace the subject directories named like SAIS* with your own list.<br>
>     <br>
>     <br>
>     <div class="moz-cite-prefix">On 11/15/2013 02:28 PM, Eshita Shah
>       wrote:<br>
>     </div>
>     <blockquote
> cite="mid:caewtdbj-hqvrsskd1lxdhhs_-duith2oro__g4+qzirgw-d...@mail.gmail.com"
>       type="cite">
>       <div dir="ltr">Hi Donna,&nbsp;
>         <div><br>
>         </div>
>         <div>Thank you, that clears up a lot. Just to clarify, my main
>           purpose is to use Caret to generate sulcal depth maps for each
>           subject and run statistical analysis (such as ANOVA) to
>           compare the results of two groups. I have completed importing
>           all my data to the fs_LR standard mesh, and now I have to
>           generate sulcal depth maps and run analyses. To do this, I am
>           planning on running the "generate depth" function from
>           PALS-B12/preborder.sh. Will this generate the appropriate
>           input parameters for running the one-way ANOVA test through
>           caret_command?&nbsp;</div>
>         <div><br>
>         </div>
>         <div>Here is a list of what's needed:&nbsp;</div>
>         <div><br>
>         </div>
>         <div>
>           <div>&nbsp;METRIC STATISTICS ONE-WAY ANOVA</div>
>           <div>&nbsp; &nbsp; &nbsp; caret_command 
> -metric-statistics-anova-one-way</div>
>           <div>&nbsp; &nbsp; &nbsp; &nbsp; 
> &nbsp;&lt;fiducial-coord-file&gt;</div>
>           <div>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&lt;open-topo-file&gt;</div>
>           <div>&nbsp; &nbsp; &nbsp; &nbsp; 
> &nbsp;&lt;distortion-metric-shape-file&gt;</div>
>           <div>&nbsp; &nbsp; &nbsp; &nbsp; 
> &nbsp;&lt;distortion-column-number&gt;</div>
>           <div>&nbsp; &nbsp; &nbsp; &nbsp; 
> &nbsp;&lt;output-file-names-prefix&gt;</div>
>           <div>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;... &nbsp; &nbsp;</div>
>           <div>&nbsp; &nbsp; &nbsp; &nbsp; 
> &nbsp;&lt;metric-file-names&gt;</div>
>         </div>
>         <div><br>
>         </div>
>         <div>After the import of the data into fs_LR mesh, I have
>           multiple coord files, shape files, and closed topo files. I do
>           not have specific paint or border files. So I am not exactly
>           sure how to exclude the paint files that label the medial wall
>           from my analysis, like you stated previously. I found a
>           command in postborder.sh that converts the closed topo file
>           into an open topo file using the roi file that's generated for
>           the medial wall. Any guidance on doing that would be
>           appreciated.&nbsp;</div>
>         <div><br>
>         </div>
>         <div>Please let me know if I'm going on the right track to
>           generate the sulcal depth maps and run my analyses.&nbsp;</div>
>         <div><br>
>         </div>
>         <div>Thank you,&nbsp;</div>
>         <div>Eshita</div>
>         <div><br>
>         </div>
>         <div><br>
>         </div>
>         <div>
>           <pre style="font-family:courier,'courier 
> new',monospace;font-size:14px;white-space:pre-wrap;word-wrap:break-word;margin-top:0px;margin-bottom:0px;color:rgb(0,0,0);line-height:19px">On
>  Nov 15, 2013, at 10:07 AM, Donna Dierker &lt;<a moz-do-not-send="true" 
> href="mailto:[email protected]";>[email protected]</a>&gt; 
> wrote:</pre>
>         </div>
>         <div><br>
>         </div>
>         <div>
>           <pre style="font-family:courier,'courier 
> new',monospace;font-size:14px;white-space:pre-wrap;word-wrap:break-word;margin-top:0px;margin-bottom:0px;color:rgb(0,0,0);line-height:19px">&gt;Hi
>  Eshita,
> &gt;
> &gt;topi = topology, and I hate auto-correct</pre>
>           <pre style="font-family:courier,'courier 
> new',monospace;font-size:14px;white-space:pre-wrap;word-wrap:break-word;margin-top:0px;margin-bottom:0px;color:rgb(0,0,0);line-height:19px">&gt;You
>  mean the surface_shape/metric files -- not the topology, right?
> &gt;
> &gt;When all your data is on a standard mesh, as Caret requires to do group 
> &gt;analysis (except for summary stats that are not vertex-wise, e.g., 
> gyrification 
> &gt;index), then typically the stats tests use a single mean midthickness and 
> open 
> &gt;topology for computing the areas that are used for the TFCE/cluster 
> &gt;distributions.
> &gt;
> &gt;You typically don't need to generate an open topo file for each subject 
> on the 
> &gt;standard mesh.  You have a single paint/label file that labels the medial 
> wall 
> &gt;vertices, so you can exclude them from your analysis.  Or in this case, 
> you 
> &gt;have an open topology file that will accomplish the same thing.  If 
> they're all 
> &gt;on standard mesh, then your standard open topi file should look 
> reasonable with 
> &gt;all your standard mesh midthickness surfaces.  
> &gt;
> &gt;An example of a time when you would need an open topi is when you want 
> the 
> &gt;gyrification index computed on the native mesh.  Then you can use a 
> strategy 
> &gt;like the <a moz-do-not-send="true" 
> href="http://PALS_B12.LR/postborder.sh";>PALS_B12.LR/postborder.sh</a> 
> &gt;(<a moz-do-not-send="true" rel="nofollow" 
> href="http://brainmap.wustl.edu/pub/donna/FREESURFER/SCRIPTS/2011_10/PALS_B12.LR/postborder.sh";
>  
> style="color:rgb(160,30,30)">http://brainmap.wustl.edu/pub/donna/FREESURFER/SCRIPTS/2011_10/PALS_B12.LR/postborder.sh</a>
> &gt; ; login pub, password download) uses in the freesurfer to PALS pipeline, 
> which 
> &gt;essentially writes a border around the standard mesh medial wall; 
> "unprojects" 
> &gt;the border on the standard mesh midthickness; and then projects it on the 
> &gt;native mid thickness.  When you do that, you need to project to/from the 
> &gt;spherical or ellipsoid, so that your medial wall border points don't get 
> hosed.
> &gt;
> &gt;You can use your own study-specific mean midthickness, but then you 
> should 
> &gt;compute your own mean distortion metric to go with it.  Besides being a 
> bit of 
> &gt;a hassle, it strikes me that your results are slightly less comparable to 
> &gt;others computed on the fs_LR standard mesh that used the more standard 
> Conte69 
> &gt;mean mid thickness/distortion.  I don't use study-specific files for this 
> &gt;purpose, unless the populations are so different (e.g., baby vs adult) 
> that you 
> &gt;can't use the adult.
> &gt;
> &gt;Visualization is another story.  I almost always show the study-specific 
> mean 
> &gt;midthickness for each group in morphometry studies.
> &gt;
> &gt;Donna</pre>
>         </div>
>         <div><br>
>         </div>
>         <div><br>
>         </div>
>       </div>
>       <div class="gmail_extra"><br>
>         <br>
>         <div class="gmail_quote">On Thu, Nov 14, 2013 at 1:38 PM, Eshita
>           Shah <span dir="ltr">&lt;<a moz-do-not-send="true"
>               href="mailto:[email protected]"; 
> target="_blank">[email protected]</a>&gt;</span>
>           wrote:<br>
>           <blockquote class="gmail_quote" style="margin:0 0 0
>             .8ex;border-left:1px #ccc solid;padding-left:1ex">
>             <div dir="ltr">
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;margin-top:0px;word-wrap:break-word"><font
>  face="arial, helvetica, sans-serif">Hi Donna, </font></pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;margin-top:0px;word-wrap:break-word"><font
>  face="arial, helvetica, sans-serif">
> 
> </font></pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;margin-top:0px;word-wrap:break-word"><font
>  face="arial, helvetica, sans-serif">Thank you for your help. From what I 
> understand, the topology files from each subject have to be compiled (using 
> caret_command -metric-composite) into one, and that file is then entered into 
> the ANOVA test. My question however, is regarding the generation of the open 
> topo files for each subject. I have used freesurfer_to_fs_LR pipeline, and 
> I'm wondering if the topo files generated (there is only one for each 
> subject) are indeed the open topo file, because looking at the script for 
> freesurfer_to_fs_LR it looks like it is the closed topo file. Any advice on 
> how to obtain an open topo file?</font></pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;margin-top:0px;word-wrap:break-word"><font
>  face="arial, helvetica, sans-serif">
> </font></pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;margin-top:0px;word-wrap:break-word"><font
>  face="arial, helvetica, sans-serif">Also, to clarify, the first parameter in 
> the ANOVA test is a fiducial coord file. I have used caret_command 
> -surface-average to generate an average fiducial file for each hemisphere. Is 
> this correct?</font></pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;margin-top:0px;word-wrap:break-word"><font
>  face="arial, helvetica, sans-serif">
> </font></pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;margin-top:0px;word-wrap:break-word"><font
>  face="arial, helvetica, sans-serif">Please let me know. </font></pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;margin-top:0px;word-wrap:break-word"><font
>  face="arial, helvetica, sans-serif">
> 
> 
> </font></pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;margin-top:0px;word-wrap:break-word"><font
>  face="arial, helvetica, sans-serif">Thanks,</font></pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;margin-top:0px;word-wrap:break-word"><font
>  face="arial, helvetica, sans-serif">Eshita </font></pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;font-family:courier,'courier
>  new',monospace;margin-top:0px;word-wrap:break-word">
> </pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;font-family:courier,'courier
>  new',monospace;margin-top:0px;word-wrap:break-word"><pre 
> style="font-family:courier,'courier 
> new',monospace;white-space:pre-wrap;word-wrap:break-word;margin-top:0px;margin-bottom:0px"><span
>  
> style="color:rgb(34,34,34);font-family:arial;font-size:small;line-height:normal;white-space:normal">On
>  Wed, Nov 13, 2013 at 10:50 PM. Donna Dierker wrote:&nbsp;</span></pre></pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;font-family:courier,'courier
>  new',monospace;margin-top:0px;word-wrap:break-word">&gt;Hi Eshita,
> </pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;font-family:courier,'courier
>  new',monospace;margin-top:0px;word-wrap:break-word">&gt;
> &gt;I always use the open topology for this purpose (i.e., excludes only 
> medial 
> &gt;wall vertices).  The files here will be helpful:</pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;font-family:courier,'courier
>  new',monospace;margin-top:0px;word-wrap:break-word">&gt;<a 
> moz-do-not-send="true" rel="nofollow" 
> href="http://brainmap.wustl.edu/pub/donna/FREESURFER/SCRIPTS/2013_11/TFCE_164k/";
>  style="color:rgb(160,30,30)" 
> target="_blank">http://brainmap.wustl.edu/pub/donna/FREESURFER/SCRIPTS/2013_11/TFCE_164k/</a>
> &gt;login pub
> &gt;password download
> &gt;
> &gt;You can get them all in this zip file:
> &gt;
> &gt;<a moz-do-not-send="true" rel="nofollow" 
> href="http://brainmap.wustl.edu/pub/donna/FREESURFER/SCRIPTS/2013_11/TFCE_164k.zip";
>  style="color:rgb(160,30,30)" 
> target="_blank">http://brainmap.wustl.edu/pub/donna/FREESURFER/SCRIPTS/2013_11/TFCE_164k.zip</a>
> &gt;
> &gt;Just to explain what is going on, the areas in the TFCE/cluster 
> computations 
> &gt;are computed on the Conte69 mean mid thickness, with the open topo file 
> &gt;(excluding medial wall).  The distortion maps pump up the areal value 
> where 
> &gt;substantial smoothing occurs as a result of averaging individuals' 
> coordinate 
> &gt;files (e.g., high 3D variability).  The intent is to make the areas more 
> like 
> &gt;an individual's area would be in that region.  For folks not attuned to 
> what 
> &gt;you are doing, this is during group analysis.</pre>
>               <pre 
> style="line-height:19px;font-size:14px;white-space:pre-wrap;margin-bottom:0px;font-family:courier,'courier
>  new',monospace;margin-top:0px;word-wrap:break-word">&gt;
> &gt;Cheers,
> &gt;
> &gt;Donna
> </pre>
>               <div>
>                 <div class="h5">
>                   <div>&gt;</div>
>                   <div class="gmail_extra">
>                     <div class="gmail_quote">&gt;On Tue, Nov 12, 2013 at
>                       1:18 PM, Eshita Shah <span dir="ltr">&lt;<a
>                           moz-do-not-send="true"
>                           href="mailto:[email protected]"; 
> target="_blank">[email protected]</a>&gt;</span>
>                       wrote:<br>
>                       <blockquote class="gmail_quote" style="margin:0px
>                         0px 0px
> 0.8ex;border-left-width:1px;border-left-color:rgb(204,204,204);border-left-style:solid;padding-left:1ex">
>                         <div dir="ltr">Hello,&nbsp;
>                           <div><br>
>                           </div>
>                           <div>Thanks for your input. I successfully was
>                             able to use freesurfer_to_fs_LR Pipeline to
>                             import my FreeSurfer files into caret,
>                             however when I try running ANOVA, it asks
>                             for certain files that have not been
>                             generated by the pipeline. Specifically, how
>                             do I generate the
>                             "distortion-metric-shape-file" that is being
>                             asked for? Lastly, is the .topo file that is
>                             generated via the pipeline the open topo
>                             file or closed? Previously I was able
>                             generate the closed topo file, so I'm not
>                             sure if the freesurfer_to_fs_LR pipeline
>                             does the same. The parameter required for
>                             the ANOVA analysis is the open topo 
> file.&nbsp;</div>
>                           <div><br>
>                           </div>
>                           <div>Thank you,&nbsp;</div>
>                           <span><font color="#888888">
>                               <div>Eshita Shah&nbsp;</div>
>                             </font></span>
>                           <div>
>                             <div>
>                               <div>
>                                 <div class="gmail_extra"><br>
>                                   <br>
>                                   <div class="gmail_quote">On Thu, Nov
>                                     7, 2013 at 4:12 PM, Rouhollah
>                                     Abdollahi <span dir="ltr">&lt;<a
>                                         moz-do-not-send="true"
>                                         href="mailto:[email protected]";
>                                         
> target="_blank">[email protected]</a>&gt;</span>
>                                     wrote:<br>
>                                     <blockquote class="gmail_quote"
>                                       style="margin:0px 0px 0px
> 0.8ex;border-left-width:1px;border-left-color:rgb(204,204,204);border-left-style:solid;padding-left:1ex">
>                                       <p dir="ltr">Hi<br>
>                                         Actually the code import the
>                                         original data from freesurfer to
>                                         caret then automatically you
>                                         will have different node number
>                                         for different subjects and
>                                         hemispheres. To have the same
>                                         mesh you can use
>                                         Freesurfer_to_fs_LR Pipeline
>                                         
> [remainder of message body omitted; too large]
> 
> _______________________________________________
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> 
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