Dear Feng,
 
Not sure about your problem with topp - what operating system are you using?  Are there extra mac or windows-derived characters at the end of the line?  Have you accidentally saved the file using a non-plaintext editing program?
 
Otherwise...
 
'Mustang' is a straightforward and robust multiple structural superposition/alignment program for 2 or more structures, and can be downloaded from http://www.cs.mu.oz.au/~arun/mustang .  It works well for very diverged structures.
 
'Superpose' comes with the ccp4i distribution and is very simple to use for 2 structures, although doesn't work so well at a high degree of divergence or for "its mostly a polyalanine model and the stereochemistry is a bit dodgy" type situations.
 
Cheers,
James
 
Dr. James Irving
NH&MRC C.J. Martin Fellow
Division of Structural Biology
Wellcome Trust Centre for Human Genetics
Oxford University
Roosevelt Drive
Headington,
Oxford OX3 7BN
UK
email: [EMAIL PROTECTED]
 

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