not sure whether this option has been mentioned before ... i think what we really would like to do is decide by the quality of the density. i see that this is difficult.
so, short of that ... how about the figure of merit in refinement ? wouldn't the fom reflect how useful our data really are ? ingo On 03/03/2011 12:29, Roberto Battistutta wrote: > Dear all, > I got a reviewer comment that indicate the "need to refine the structures at > an appropriate resolution (I/sigmaI of >3.0), and re-submit the revised > coordinate files to the PDB for validation.". In the manuscript I present > some crystal structures determined by molecular replacement using the same > protein in a different space group as search model. Does anyone know the > origin or the theoretical basis of this "I/sigmaI >3.0" rule for an > appropriate resolution? > Thanks, > Bye, > Roberto. > > > Roberto Battistutta > Associate Professor > Department of Chemistry > University of Padua > via Marzolo 1, 35131 Padova - ITALY > tel. +39.049.8275265/67 > fax. +39.049.8275239 > roberto.battistu...@unipd.it > www.chimica.unipd.it/roberto.battistutta/ > VIMM (Venetian Institute of Molecular Medicine) > via Orus 2, 35129 Padova - ITALY > tel. +39.049.7923236 > fax +39.049.7923250 > www.vimm.it >
