Heparin simulates the structure of DNA and RNA, so it has nonspecific affinity towards DNA or RNA binding protein. It has also been used as DNAse or RNase inhibitor but it is not very good one.
Nian Huang, Ph.D. UT Southwestern Medical Center On Sat, Apr 9, 2011 at 7:44 PM, Alexandra Deaconescu <[email protected]>wrote: > Hello ccp4 enthusiasts: > > I am afraid this is a non-ccp4 related question. Can anyone recommend an > immobilized dsDNA chromatographic resin for purification of DNA-binding > proteins? GE seems to have something - I was wondering if people have other > recommendations? In the age of GST and His tags etc., these are not very > much used, but I do not have a tag in this case... > > Thanks a lot, > Alex >
