Ed, sorry for delay.  I was not trying to make any significant distinction
between "controllable" and "potentially controllable": from a statistical
POV they are the same thing.  The distinction is purely one of
practicality, i.e. within the current experimental parameters is it
possible to eliminate the systematic error, for example is there a
calibration step where you determine the systematic error by use of a
standard of known concentration.  The error is still controllable
regardless of whether you actually take the trouble to control it!  Note
that the experimental setup has not changed, you are merely using the same
apparatus in a different way but any random errors associated with the
measurements will still be present.

Of course if you change the experimental setup (note that this potentially
includes the experimenter!) then all bets are off!  It's very important to
describe the experimental setup precisely before you attempt to
characterise the errors associated with a particular setup.

BTW I agree completely with Kay's analysis of the problem: as he said "you
are sampling (once!) a statistical error component".  This is what I was
trying to say, he just said it in a much more concise way!  This random
(uncontrollable) error then gets propagated through the sequence of steps
in the experiment along with all the other uncontrollable errors.

Cheers

-- Ian


On 11 March 2013 19:04, Ed Pozharski <[email protected]> wrote:

> Ian,
>
> thanks for the quick suggestion.
>
> On Mon, 2013-03-11 at 18:34 +0000, Ian Tickle wrote:
> > Personally I tend to avoid the systematic vs random error distinction
> > and think instead in terms of controllable and uncontrollable errors:
> > systematic errors are potentially under your control (given a
> > particular experimental setup), whereas random errors aren't.
> >
> Should you make a distinction then between controllable (cycling cuvette
> in and out of the holder) and potentially controllable errors
> (dilution)?  And the latter may then become controllable with a
> different experimental setup?
>
> Cheers,
>
> Ed.
>
> --
> I don't know why the sacrifice thing didn't work.
> Science behind it seemed so solid.
>                                     Julian, King of Lemurs
>
>

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