Trying not to state the obvious but...HIV protease -----Original Message----- From: CCP4 bulletin board [mailto:[email protected]] On Behalf Of Keller, Jacob Sent: Friday, 28 February 2014 8:43 a.m. To: [email protected] Subject: [ccp4bb] Large Conformational Change Upon Binding Ligand...
Dear Crystallographers, Does anyone know of good examples of large, reversible conformational changes occurring between ligand-free and -bound states? Could also be a non-relevant molecule binding, like sulfate or something inducing dubiously -relevant changes. I already know of the calmodulin and periplasmic binding protein families, but does anyone know of others out there? All the best, Jacob Keller ******************************************* Jacob Pearson Keller, PhD Looger Lab/HHMI Janelia Farms Research Campus 19700 Helix Dr, Ashburn, VA 20147 email: [email protected] *******************************************
