Hi all, I am trying to refine a structure in CCP4 and the final R factor is about 1% lower than the initial but for the first “task/cycle” within the same refinement job in CCP4, R factor starts off higher than the input data R factor.
I have a structure with multiple sugars attached, I did the first refinement after building the sugars with a lib file that worked well and the R factor did go down significantly but every time I try to refine again to lower it more, the above happens. Any suggestions? Thank you. Remie
