I don’t know about the myth thing, but I remember Martha Teeter describing 
pentagons of waters in crambin.

Here’s a reference:

Water Structure of a Hydrophobic Protein at Atomic Resolution: Pentagon Rings 
of WaterMolecules in Crystals of Crambin      M. M. Teeter      Proceedings of 
the National Academy of Sciences of the United States of America, 1984, 81(1), 
6014-6018.

Ron

From: CCP4 bulletin board <[email protected]> On Behalf Of Vijaykumar 
Pillalamarri
Sent: Friday, September 27, 2019 4:34 AM
To: [email protected]
Subject: [ccp4bb] Reg: water pentagon at dimer interface

Dear Community,

I solved the structure of a protein from vibrio. There are two molecules in the 
asymmetric unit of this protein. At the dimer interface, the C-termini of both 
the chains interact with each other with the help of five water molecules that 
form a pentagon. I have attached an image showing both the chains and stereo 
image of dimer interface in the inset. I was wondering if there is any 
significance to this or if there is any relevant literature that explains this 
behavior.

Thank you
Vijaykumar Pillalamarri
C/O: Dr. Anthony Addlagatta
Principal Scientist
CSIR-IICT, Tarnaka
Hyderabad, India-500007
Mobile: +918886922975

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