There are literature shown this kind of possiblity to have dimerization via water mediated interactions. But look whether in solution also they could form dimer or not. How to figure out it is not non specific, it is physiological relevant.
Cheers SR On Fri, Sep 27, 2019, 5:04 PM Vijaykumar Pillalamarri < vijaypkuma...@gmail.com> wrote: > Dear Community, > > I solved the structure of a protein from vibrio. There are two > molecules in the asymmetric unit of this protein. At the dimer interface, > the C-termini of both the chains interact with each other with the help of > five water molecules that form a pentagon. I have attached an image showing > both the chains and stereo image of dimer interface in the inset. I was > wondering if there is any significance to this or if there is any relevant > literature that explains this behavior. > > Thank you > Vijaykumar Pillalamarri > C/O: Dr. Anthony Addlagatta > Principal Scientist > CSIR-IICT, Tarnaka > Hyderabad, India-500007 > Mobile: +918886922975 > > ------------------------------ > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 > ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
