Indeed they have been observed in quite a number of high resolution structures.
http://www.ruppweb.org/Garland/gallery/Ch12/pages/Biomolecular_Crystallography_Fig_12-28.htm Chees, BR From: CCP4 bulletin board <[email protected]> On Behalf Of Ronald E. Stenkamp Sent: Friday, September 27, 2019 17:22 To: [email protected] Subject: Re: [ccp4bb] Reg: water pentagon at dimer interface I don’t know about the myth thing, but I remember Martha Teeter describing pentagons of waters in crambin. Here’s a reference: Water Structure of a Hydrophobic Protein at Atomic Resolution: Pentagon Rings of WaterMolecules in Crystals of Crambin M. M. Teeter Proceedings of the National Academy of Sciences of the United States of America, 1984, 81(1), 6014-6018. Ron From: CCP4 bulletin board <[email protected] <mailto:[email protected]> > On Behalf Of Vijaykumar Pillalamarri Sent: Friday, September 27, 2019 4:34 AM To: [email protected] <mailto:[email protected]> Subject: [ccp4bb] Reg: water pentagon at dimer interface Dear Community, I solved the structure of a protein from vibrio. There are two molecules in the asymmetric unit of this protein. At the dimer interface, the C-termini of both the chains interact with each other with the help of five water molecules that form a pentagon. I have attached an image showing both the chains and stereo image of dimer interface in the inset. I was wondering if there is any significance to this or if there is any relevant literature that explains this behavior. Thank you Vijaykumar Pillalamarri C/O: Dr. Anthony Addlagatta Principal Scientist CSIR-IICT, Tarnaka Hyderabad, India-500007 Mobile: +918886922975 _____ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB <https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1> &A=1 _____ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB <https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1> &A=1 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
