Hi I have a weird question. Is it possible to incorporate or mutate amino acid residues at the interface of two interacting surfaces in a multi subunit protein complexes hoping it to form a disulfide bond making the over all complex more stable for downstream structural studies ?
Is there any sort of literature available where creating these types of modification or kind of protein engineering helped in making a more stable complex, eventually helping in further structural studies by x-ray or cryoem ? Best kahkashan ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
