Hi Firdous,

I have read a fair amount of papers about ATP-dependent chromatin remodelers in 
which ADP-BeF3 is often cited. It is made as follows (quoting from one of these 
papers): "ADP-BeF3 was prepared as a 10x stock (10 mM ADP, 30 mM BeSO4, 150 mM 
NaF, 10 mM MgCl2), freshly before use."

So the trick is to get all you need from a mixture of soluble compounds, 
instead of from only one poorly soluble salt. Not sure this will work the same 
with Al instead of Be, but it’s easy enough to try: use any known-soluble salt 
of Al instead of this BeSO4, and see if it works. NaF is extremely toxic, so 
use adequate protective measures (PPE, hood, etc.).

Good luck,

Guillaume


> On 21 Jun 2022, at 19:38, Firdous Tarique <[email protected]> wrote:
> 
> Hi
> 
> Sorry for the off topic question but can anybody please suggest how to 
> dissolve Aluminium Fluoride in water ? I know it has little solubility in 
> water but have seen people using AF3 for their structural studies (ADP + AF3 
> as ATP analogue). Is there any other solvent where they have made AF3 
> solution or is there some trick to dissolve it in water?.
> 
> Thanks
> 
> Firdous
> 
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