Good guestion Diane...yes there is validity for profiling the genetic combination of that breeding...but as in everything, we must understand the value of each test measurement.
I had asked OFA regarding profiling litter and the specific predictive value.� They have completed data analysis on litter profiles on goldens, labs, GS and Rotts at 4-6 months of age.� They indicated that CKCSs would most likely fall in this predictive range. The purpose for having a litter profiled is that this would give you a look at that genetic combination of that breeding and their possible recessive traits. The results are: Sensitivity= 80% reported A rate that indicates the percent of dogs with the disease who are CORRECTLY classified as having the disease. Specificity= 97% reported A rate that indicates the percent of dogs WITHOUT disease who are correctly classified as not having the disease Predictive Value: High Sensitivity + High Specificity Rates = Excellent Predictive Value; this has good predictive values. As you can see this has a very high specificity level of 97%...the negative is that you have a 80% sensitivity rate indicating 20% chance of false positives.so you may remove dogs from your breeding program that are not truly problematic. That is why it is important...I feel to re-evaluate at 2 years of age and maybe at 5 years of age. This is Just Food for Thought... Kathy Yonkers Stuarthome CKCS ========================================================"Magic Commands": to stop receiving mail for awhile, click here and send the email: mailto:[EMAIL PROTECTED]?body=SET%20CKCS-L%20NOMAIL to start it up gain click here: mailto:[EMAIL PROTECTED]?body=SET%20CKCS-L%20MAIL E-mail [EMAIL PROTECTED] for assistance. Search the Archives... http://apple.ease.lsoft.com/archives/ckcs-l.html All e-mail sent through CKCS-L is Copyright 2002 by its original author.
