Based on Gil's tracking new cases (never seen before by cardiologist)

In 1994, total number of dogs examined were 172. Of those 172 dogs, 35% had
a murmur by age 3.

In 2001, total number of new dogs examined were 248. Of those dogs, 30% had
a murmur by age 3.

Results of this study: 5% drop in murmur detection by age 3 from new cases
examined in 1994 and in 2001

In 1994, 20% of the new cases had a murmur by 5 to 5.5 years
In 2001, 30% of the new cases had a murmur by 6 to 8 years

Results are positive, stay the course. Not realistic to expect to eliminate
this complicated, polygenetic disease from cavaliers. However, we can
continue to increase the age of early development.  His research already
shows over the last 7 years that we had a 5% drop by age 3. That is
progress!

>From other foreign studies with larger samples over 10 year period, the
average age a murmur is detected by a cardiologist is:
8% at 3 years, 24% by 5 years, 30 to 40% by 8 years, and 90% by 10 years.

He also said if he had a dog clear at 3 but discovered a murmur at 3.5 years
that he still should be a part of the breeders breeding program because to
drop all dogs that have a murmur at 3.5 years of age would amplify too many
other negative traits and create new problems that don't exist now in our
breed. In his opinion, you have a higher chance of reducing carriers of MVD
by breeding 4 year olds that are heart clear. However, he said 4 is too old
to breed for the first time. So continue what we are doing because it is
making a difference in the age of early onset.

Treatment suggestions:
murmur, no signs, no treatment
shows symptoms, use lasix
moderate heart enlargement, use ace inhibitor
severe, use all, every 12 hours - lasix, aldactone,plus "ace inhibitors" -
enalapril & beneazepril & digoxin
To sleep better, apply nitroglycerin ointment at night and wear a protected
glove when rubbing in on chest. Remove 12 hears later.

Take incremental approach with food and exercise.

Food: continue the same brand of dog food they enjoyed prior to diagnosis
vs. salt restricted food , however, restrict salt from treats like no more
peanut butter or chicken skin. Most important for them to keep eating.

Exercise: no running at moderate enlargement
severe enlargement,  must be very restrictive, pick up and take outside to
potty

I have given a summary from my notes since he gave no hand-outs and hope you
find this helpful.

Patricia Powers Pratt Cavaliers


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