Hi all.  

I just returned from MDAnderson.  It was a whirlwind trip - as 
getting there was quite challenging.   The Houston airport closed 
(which is rare) on Wednesday due to very bad storms and flooding - so 
I was delayed by about three hours in getting there.   
All went well - as usual and it was an uneventful trip.

However, I spoke with Dr. Giles yesterday and he wants me to get the 
word out to the CML community.  He opened a new trial yesterday for 
CML patients that have lost their response to Gleevec . . . (maybe 
someone who is FISH positive, or is no longer negative on cyto).  He 
is looking for recruits if anyone has the need.  The trial consists 
of combining Gleevec with the new AMN107 compound.   It sounds very 
exciting and is yet another option for all of us.

More exciting however, is the VX trials - which I believe Anjana has 
posted about on the Asian list.  Dr Giles said it shows incredible 
promise for eradicating the dreaded T3151 mutation - that to date - 
no other compound appears to have any effect on.   He is recruiting 
for this trial as well.

If you have any interest, you can contact his PA - Mary Alma Welch at 
[EMAIL PROTECTED]  You can also reach her at MDAnderson via the 
leukemia clinic - at 713-792-8760.

This is an amazing time for CML patients - with many options to look 
at should we need it!

I'll continue to keep you all posted on my results.  It was a 
delightful time to be at the hospital.   Everything was awash in 
Christmas and holiday finery.   Each floor was decorated with holiday 
decorations, carolers were singing and even 'Santa' visited in the 
bone marrow clinic - handing out candy canes, cookies and juice.  It 
made a difficult day much more tolerable.   The facility truly goes 
out of their way to make every patient feel special!

Hugs to all of you!
Love,
Barb






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