Rebecca, I have gone from 600 mg (started in 1999) down to 400 mg this past Dec. My PCR was <.01% and the doctor thought it would be safe to try the reduction. I was having problems with the acid making me sick of my stomach and I have definitely felt better. I will have a BMA in June to determine if the changed dosage is holding my molecular remission. I haven't seen much info on reduced dosages and believe I am an experiment in progress. I'll report to the group about my June results are completed. Let me know if you learn anything else.
Thanks, Gay Bratton -----Original Message----- From: [email protected] [mailto:[EMAIL PROTECTED] On Behalf Of Rebecca Russo Sent: Monday, February 25, 2008 9:31 PM To: [email protected] Cc: [EMAIL PROTECTED]; [EMAIL PROTECTED] Subject: [CMLHope] Re: Lowering your dose Has anyone gone from 800mg down to 600mg? I've been advised that a reduction can be correlated with a loss of efficacy of the drug which can lead to relapse. Has anyone had this experience? Also, does anyone know if there's a correlation between the patient's weight and the amount of Gleevec necessary to be effective? Thanks, Rebecca --~--~---------~--~----~------------~-------~--~----~ [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [EMAIL PROTECTED] For more options, visit this group at http://groups.google.com/group/CMLHope -~----------~----~----~----~------~----~------~--~---
