My husband who became PCRU in 8 months after he was diagnosed with CML (2004) had terrible side effects with Gleevec. After sticking with Gleevec for 2 years his doctor at UCLA finally put him on Sprycell (dasatinib) two years ago. The side effects immediately became fewer and he is much happier on dasatinib. Our 2 cents worth.
Tanya On Sep 21, 2008, at 7:26 PM, sheila wrote: > > Hello! I don't post much, but I really need some help here. To make a > long story short I was disagnosed 3 years ago in August 2005 with cml > at Mayo Clinic at first I was diagnosed by a local oncologist with > myleofibrosis at this time I was a month past my 37th birthday. That > doc sent me on to Minnesota where they did another bmb and found that > I had the philly chromosome. I started gleevec 400 mg right away and > was monitored by a doc from Indy and he kept in touch with Mayo. I > responded great at first, at diagnosis I was 98% philly + with in 3 > months I was down to lower digits and Mayo was very happy and told me > they would see me in 6 months, well by December my white count went > too low so my Indy doc had me taking gleevec everyother day. This > bounced my white count back up but it also started my phiily's to > increase and my platelets to rise. So when I went back to Mayo in > March 2006 the philly's were on the rise so they increase the gleevec > to 800 mgs and monitored me very close and I was getting every other > week shots for the low white count until finally by Sept 2006 I was > finally zero with my FISH test. So since I have stayed on 800mgs then > they started doing a pcr test and I have yet to reach zero I am at > 0.05% I have the FISH and the pcr test done every 3 months, I have > blood drawn and sent up to Mayo then I drive 8 hours from Indiana to > get my results (crazy!) I have a tendency to go up a little then 3 > months later go down then 3 months I go up a little then back down, > they gave me a graph so I could see this. I have been zero on the > FISH since 2006 and they tell me that this is the test that they > really go by but now the Mayo doc tells me he wants me to switch from > gleevec to dasatinib. My Indy doc and me talked about it before and > we both agreed that "if it ain't broke don't fix it" so Mayo is > letting me decide what to do but they highly recommend the switch. I > have very few side affects with the gleevec and the Mayo doc told me > all the side affects from the dasatinib which totally freaked me out. > My husband thinks I should stay on the gleevec and so do I, but I just > don't know if that really is the right decision and that's where I > need some help here! Anyone's opinion would be greatly appreciated. > > Thanks! > > Sheila > > > --~--~---------~--~----~------------~-------~--~----~ [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [EMAIL PROTECTED] For more options, visit this group at http://groups.google.com/group/CMLHope -~----------~----~----~----~------~----~------~--~---
