Hello Ann, I took gleevec for 5 years. The side effects became unbearable. and I switched to tasigna. However, during the 4th year, I was advised to take a break and did so for 10 weeks. I have been and held the PCRU the whole time. I do agree with Trey, that you should have a blood level test done. Mine came back at 1100 - v ery close to normal. I consulted with Druker and my oncologist ( and was monitored closely). My side effects went totally away in a matter of 2 weeks. It was the best time of my life!! I resumed the gleevec ( always at 400 mg only) and in a matter of weeks, the side effects were back. My oncologist decided to put me on tasigna because he classified me intolerant. So, Psycollgically, it did do me a world of good. I would do the test first, and as well, make sure you have the permission and monitoring of your oncologist. Good luck. Barb in AZ
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