Just wondering if the PE ever really goes away completely. I've had it for about two months now, not enough to interfere with regular activities really, but still noticeable. I've had two chest x-rays, both indicating the PE, and actually I've decreased my Sprycel from 140mg to 100mg partially to address that issue. Everything I read tells me that having the fluid drained is a last resort b/c it just returns almost immediately. I'm hoping that over time the body just absorbs the fluid, but I imagine once you've had PE, it will return from time to time. What do you think? -janeaye
On Mar 15, 12:03 pm, Sean <[email protected]> wrote: > Hello all, > > Been a long long time since I last wrote to this group. Thought I'd > check in. I was dxd in Oct 2002 when I was 21 years old. My WBC at > time of diagnosis was 498,000. Since that time I've been on Gleevec > for the first 6.5 years or so (between 400 - 800mg but mostly the > latter), and I've been on Sprycel for the past year, first at 140mg > and now at 170mg. I'm young, so I suppose that helps me tolerate the > high doses, as I had virtually no problems on Gleevec for all those > years other than minor fluid retention in the ankles. I've been CCR > for a long time but guess I forgot to tell Zavie about that :) > > My PCR tests have been hovering between 0.08% (8x10^-4)and lower, the > most recent at 0.0012% (1.2x10^-5). The switch to Sprycel was an > effort to get to PCRU, but now I've got pleural effusion. It's not > particularly noticeable, but chest x-ray confirmed it along with > increased shortness of breath climbing stairs, etc. Doc said to switch > to 170mg 6 days/week instead of 7. If this doesn't work he may want to > switch me to nilotinib, but that doesn't sound like a fun drug to me. > > Question is: Is PCRU really that worth it? I think I'd rather stay on > a lower dose of Sprycel, rid myself of the fluid as a result, than > switch to yet another drug. The PCR results are already really low. > > Thoughts? > > Hope everyone is doing well, > Sean -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope
