My onc has told me that if my CBC and BCR-ABL all come back normal, there is no 
need for BMB. If those numbers start changing, especially in the bcr-abl, 
that's when I have had to go back and have a BMB. I was on Gleevec for 1 1/2 
years when my numbers starting going up on the bcr-abl, that's when I had the 
BMB and was switched to Sprycel. I think these "expensive" blood tests are very 
accurate and will give the onc a good indication of whether a BMB is necessary. 

Lenda 
----- Original Message ----- 
From: [email protected] 
To: [email protected] 
Sent: Wednesday, April 14, 2010 10:50:47 AM GMT -06:00 US/Canada Central 
Subject: [CMLHope] BMB's - still necessary or "the way we have always done it"? 

Just wondering. Am I the only one here who's never had a BMB? 
About a year into my little journey my onc mentioned one. But when I asked what 
we would learn from a BMB that would alter my course of treatment he didn't 
really have an answer. (My CBC numbers all jumped to the normal range within 2 
months of starting Gleevec. - Well, excluding CD4/CD8 counts anyway which are 
part of my much longer story.) So not being that curious I/we opted to continue 
blood counts and BCR-ABL testing as long as things are stable. He opined that 
he wished he had a baseline but that was about it. 
Patrick 


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