Go to http://googlegroups.com and click on the Forgot Password link at the bottom. It will tell you how to retrieve your password.
Rob On Sat, Sep 18, 2010 at 11:24 PM, judy <[email protected]> wrote: > its been a couple of years since I signed in and forgot my pass work andy > idea of how I can get it back???? JUDY > > ------------------------------ > *From:* Rob <[email protected]> > *To:* [email protected] > *Sent:* Sat, September 18, 2010 10:34:54 PM > *Subject:* Re: [CMLHope] Cure possible for CML? > http://community.lls.org/thread/4670;jsessionid=762495A7D980475849018A307757F5F6 > > That is a really interesting story especially since Zileuton is already > FDA approved and on the market. > > Rob > > On Sat, Sep 18, 2010 at 2:09 PM, Ricardo Gadelha < > [email protected]> wrote: > >> >> http://community.lls.org/thread/4670;jsessionid=762495A7D980475849018A307757F5F6 >> >> http://www.bangordailynews.com/detail/108012.html >> >> >> http://ellsworthmaine.com/site/index.php/2008031313384/Lab-Report/Lab-Is-Home-to-Chinese-Scientists-Leukemia-Research.html >> http://www.bangordailynews.com/detail/108012.html >> >> >> Jackson Lab work IDs gene; asthma drug foils cancer cells >> Cure possible for one type of leukemia >> >> >> *By Meg Haskell* <[email protected]> >> BDN Staff 6/10/09 >> >> A physician and researcher affiliated with The Jackson Laboratory in Bar >> Harbor says he may have identified a cure for the most common form of human >> leukemia. >> >> Dr. Shaoguang Li, now conducting research at the University of >> Massachusetts Medical School in Worcester, has identified a specific gene >> that supports the development of chronic myeloid leukemia, as well as a drug >> treatment that targets that gene to short-circuit the proliferation of >> leukemic blood cells. >> >> In a telephone interview Tuesday, Li said the results of his study, >> published in the current issue of the journal Natural Genetics, is good news >> for victims of chronic myeloid leukemia. >> >> “The power of this strategy is for curing the disease, not just >> controlling it,” Li said. >> >> The gene, called Alox5, allows leukemia-producing stem cells to develop >> and proliferate, Li said. >> >> In research at The Jackson Laboratory, Li studied mice that had been >> specially bred to lack the Alox5 gene. >> >> “If you remove the gene from a mouse, you don’t see leukemia develop,” he >> said. That’s because Alox5 is somehow tied to the development of cancer stem >> cells, the precursors to leukemia, he said. >> >> Li also studied normal mice with leukemia, targeting the Alox5 gene with >> the drug Zileuton, which is approved for treating asthma. Zileuton >> successfully blocked the gene’s production of an enzyme that turns cancer >> stem cells into full-blown leukemia cells. >> >> “When you block the gene’s function by using the drug … you’re going to be >> leukemia-free,” Li said. >> >> Mice treated with a combination of Zileuton and Gleevec, the most >> effective treatment currently available for chronic myeloid leukemia, fared >> even better than mice treated with either medication alone. >> >> Li said Zileuton must now be studied in human clinical trials before it >> can be prescribed for leukemia patients. >> >> “A lot of patients will be interested” in participating in those trials, >> he forecast. “This is for a cure.” >> >> Already, he said, he has been contacted by the father of a young leukemia >> patient about participating in a clinical trial. The drug’s current approval >> for use in treating asthma should fast-track the clinical studies, he said, >> but he declined to speculate on a timeline. >> >> Li said there are larger implications as well. >> >> “Now we know we can target cancer stem cells without damaging other stem >> cells,” he said. “Without this gene, normal blood can be produced, but the >> leukemia disappears.” >> >> In a news release issued earlier this week, The Jackson Laboratory said it >> is seeking “patent protection” on the treatment developed by Li and his >> research colleagues at the University of Massachusetts Medical Center and >> the Dana-Farber Cancer Institute at the Harvard Medical School. >> >> Li, who retains adjunct professor status at The Jackson Laboratory, said >> the Bar Harbor lab could “benefit a great deal” from his research findings. >> >> -- >> [CMLHope] >> A support group of http://cmlhope.com >> ------------------------------------------------- >> >> You received this message because you are subscribed to the Google Groups >> "CMLHope" group. >> To post to this group, send email to [email protected] >> To unsubscribe from this group, send email to >> [email protected] >> For more options, visit this group at >> http://groups.google.com/group/CMLHope > > > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at > http://groups.google.com/group/CMLHope > > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at > http://groups.google.com/group/CMLHope -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope
