It should be very interesting to have the opinion of Dr Druker about that . I always thought then 400 mg/day was the minimum dosage . Emile Fichault Dx Dec 2002 no 527 Zavie’s Club
P.S. : Someone have news of Zavie ?? ***************************************************************************************************************** From: Sheilah McCoy Sent: Saturday, June 11, 2011 8:03 AM To: [email protected] Subject: RE: [CMLHope] Digest for [email protected] - 4 Messages in 2 Topics I am an example that you do not need to follow the standard treatment dosing of 400 mg. At 400 mg I had muscle cramping so bad that it woke me at night, prevented me from doing the crafts I love to do because my hands cramped with the slightest fine movement. It even caused me to stumble at times because my feet and legs cramped so badly. I went on Gleevec on Sept 4, 2004 and after dealing with the cramping for 3 months, my Oncologist dropped my dose to 300mg in Jan of 2005. I have been on 300mg a day since then, have had a complete molecular response with no detectable bcr-abl since then. Just make sure your oncologist is following your blood work frequently. I have bloodwork drawn every 2 to 3 months, I have flow cytometry for bcr-able by FISH every 6 months and a bone marrow biopsy about every other year. I am in 100% molecular remission taking 300mg daily for the last 6 years. ************************************************************************************************************************** "Pat Elliot" <[email protected]> Jun 10 06:30PM -0700 ^ The risk is a lack of response and that could lead to multiple complications including going into blast crisis. This could put the patient's life at risk. The standard dosage is 400 mg/day. How is the patient being monitored and what have the tests shown? Has a reason been given for not following the standard protocol for CML treatment? Pat in Phoenix *************************************************************************************************************** From: [email protected] [mailto:[email protected]] On Behalf Of Dour Daze Sent: Friday, June 10, 2011 1:26 PM To: CMLHope Subject: [CMLHope] 200mg/day effective for normal male? What would you expect to transpire to a newly diagnosed cml patient chronic phase... male 6'0 if he is treated for a long period of time (more than 7 months) on 200 mg/day of Gleevec? What is the risk of the lower dosage? DD -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope
