Were they like large red pumps that stayed around for a Few weeks and they hurt to touch? On Dec 9, 2011 10:53 AM, <[email protected]> wrote:
> ** > Yes...off and on. Not a real problem though. Tom in KY > > In a message dated 12/9/2011 10:52:02 A.M. Eastern Standard Time, > [email protected] writes: > > Has anyone on sprycel run into an acne problem? > On Dec 9, 2011 10:49 AM, <[email protected]> wrote: > >> ** >> Greenie...thanks for your response. I didn't remain on Gleevec at 300mg >> long because the rash worsened. Started to affect my fingernails, etc. >> Dr's at MDA took one look and stopped it. If the Sprycel doesn't work at a >> lower level I will suggest giving Gleevec another try. Have a great >> holiday! Tom in KY >> >> In a message dated 12/8/2011 5:53:15 P.M. Eastern Standard Time, >> [email protected] writes: >> >> Tom, (1) when you started Gleevec and you received the rash how long did >> it last? (2) when they dropped you from 400 mg to 300mg did the rash start >> to go away. I started Gleevec in Feb. of 2000 with 400 mg, I also got >> the Gleevec rash and being in a study at Chicago they had no idea what to >> think of it. They gave me a cream to apply to the areas put that did not >> help. >> >> They then dropped me down to 300 mg and I've been on this amount all of >> these years. The rash lasted for about 2 months then it started to slowly >> go away and never returned. The rash covered the bottom of my feet, my >> arms, the top of my hands and all over my chest. And their were little >> bumps on the palms of hands and the bottom of my feet. I don't know if >> this info will help but this is what happened to me. Their were only 8 >> people in my study and I don't have any idea what happened to any of them. >> I've asked but they won't tell me anything. Hope this can help. >> >> greenie >> >> In a message dated 12/8/2011 10:48:38 A.M. Eastern Standard Time, >> [email protected] writes: >> >> I have just found out that I have Pleural Effusion and a little >> Pericardial Effusion apparently from my Sprycel use. I have been on >> Sprycel for about two years (100mg/day) and noticed some shortness of >> breath and chest pain. Xrays confirmed that one lung sack was about 30% >> full of fluid and an Echo Cardiogram confirmed the heart fluid buildup. I >> have just had a CT exam to further define the problems. A summary of my CML >> journey is given below. >> >> I am fortunate to have great Doctors...one at MD Anderson and one in KY >> who are heavily involved. >> >> I have several questions for those that may have been down this same >> road... >> >> 1. They put me on 50 mg of Prednisone and stopped my Sprycel >> immediately...suggesting that they will restart it at a lower dose when the >> fluid clears up. Did anyone out there have this same treatment? How do >> the lower doses do in controlling the CML? Did anyone have problems with >> Prednisone? I am generally adverse to taking lots of steroids. >> 2. Sprycel is my 3rd try at a TKI for CML. I was unable to take Gleevec >> and Tasigna successfully. If I can't tolerate Sprycel, are there any other >> experimental drugs that you are aware of that are a possibility? I know >> MDA has several studies going on in this reguard. >> 3. Do any of you have Pericardial Effusion....and if so, what was done to >> treat it? >> >> Thanks for any help you can provide. I look at this as just another >> speed bump in the CML journey and feel fortunate that we have so many >> options available for treatment. >> >> Tom in KY >> >> *Tom Dunham, BD: 8/1941* >> ** >> DX CML 12-23-2008 >> MDA Protocol: Tasigna-400mg; 2xday-1/09 >> On Flecainide for AF...still had frequent episodes >> Q PCR bone@ 0.17 on 7/09 >> Acute Pancreatitis-7/5/09 >> Stopped Tasigna-7/13/09 >> Q PCRU blood-7-29-09 ! >> Started Gleevec-400mg/day-7/31/09 >> Developed rash ~ 8/19/09 >> Rash treated with Steroids..improvement >> Rash worsens~9/22/09 >> Stopped Gleevec-9/28/09 >> Restarted Gleevec @300mg/day-10/8/09 >> Stopped Gleevec-10/13/09-toxic rash\ >> AF returned infrequently >> Q PCR bone-0.05 >> Started Sprycel @ 100mg/day-10/20/09 >> Some AF...increased FLecainde..1, 2x/day >> Q PCR bone..0.07 >> Stopped Alcohol…no AF, ½ Flecainide 2x/day >> Q PCR Blood…Non Detectible-12-13-10 >> Q PCR Bone..0.01--2-25-11 >> Q PCR Blood…Undetectible-5-19-11 >> Reduced Flecainide to 1/2 per day >> Pleural and pericardial Effusion: stopped Sprycel-12-6-'11 >> Prednisone 50mg /day to combat PE >> >> >> -- >> [CMLHope] >> A support group of http://cmlhope.com >> ------------------------------------------------- >> >> You received this message because you are subscribed to the Google Groups >> "CMLHope" group. >> To post to this group, send email to [email protected] >> To unsubscribe from this group, send email to >> [email protected] >> For more options, visit this group at >> http://groups.google.com/group/CMLHope >> >> -- >> [CMLHope] >> A support group of http://cmlhope.com >> ------------------------------------------------- >> >> You received this message because you are subscribed to the Google Groups >> "CMLHope" group. >> To post to this group, send email to [email protected] >> To unsubscribe from this group, send email to >> [email protected] >> For more options, visit this group at >> http://groups.google.com/group/CMLHope >> >> -- >> [CMLHope] >> A support group of http://cmlhope.com >> ------------------------------------------------- >> >> You received this message because you are subscribed to the Google Groups >> "CMLHope" group. >> To post to this group, send email to [email protected] >> To unsubscribe from this group, send email to >> [email protected] >> For more options, visit this group at >> http://groups.google.com/group/CMLHope > > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at > http://groups.google.com/group/CMLHope > > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at > http://groups.google.com/group/CMLHope -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. 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