Tom I am graced with Dr Talpaz one of the doctors who developed and tested
Sprycel.  I was test today at the U of M for PAH.  I was put on 50 mg of
sprycel after 7 Years on Gleevec.  After 3 months he moved me to 70 mg but
due to folliculits, which is a side affect of sprycel, he moved me back to
50 mg and is treating the folliculits with an antibiotic.  His protocol is
50 mg first.  If it works keep it there.  If it does not move to 70 mg. See
how that works.  He was adimat  not to start at 100 mg and work down.  Look
for Dr Talpaz credentials and awards for treating CML.  He is one of the
pioneers for Gleevec , Sprycel, Tasagnia.
On Dec 16, 2011 2:21 PM, <[email protected]> wrote:

> **
> Beth...I just had to stop Sprycel because of pleural effusion...when it
> gets back under control, I will go to a lower dose of Sprycel.  How did you
> arrive at 50mg?  My doc is suggesting 70mg/day...what were your side effect
> related to effusion if any?
>
> Tom in KY
>
>  In a message dated 12/16/2011 1:02:22 P.M. Eastern Standard Time,
> [email protected] writes:
>
> Great news SuzieQ - you are holding your own beautifully. I have
> qudestion for all my CMLers out there..is anyone taking sprycel at 40 mgs
> or less successfully? I am on 50 but am having some unmanageable side
> effects. I m afraid to go less fo rfear of reistance, but it' the balance
> between my sensitivity to the drugs and problematic side effects like
> elevated CPK, swelling, and needing to get and stay in remission. Any input
> would be appreciated. Beth
>
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