Susan,I take (4) 150 mg a day. As far as I know the only dosages are 150 mg and 200 mg, no 125. But yes, one 150 mg a day would be a very low dose.Here's a pretty complete rundown on side effects and reactions from the Tasigna site http://www.us.tasigna.com/patient/patient-prescribing-information.jsp I haven't had any side effects on Tasigna as opposed to a litany of nasties on Gleevec. (Maybe some of the minor ones like muscle pain but nothing I can pin on Tasigna.) Everyone as they say is different. Fasting for 3 hours twice a day to take it is a PITA.It took me 9 months to achieve complete hematologic response on Gleevec. On Tasigna it was something less than the 2 weeks before my first blood work. I had complete cytogenetic response in a couple of months. Major molecular response @ 8 months and Zeros on my brc-abl at 12 months. Since then more zeros and zeros on the chromosome analysis they decided to add. Brain bleeds are listed as a possibility so I'll be sending 324's your way (that's 18 squared. No, Marty you don't have to explain the linguistics to me - it's a joke!)And SuzieQ, you ARE a warrior. Don't be a hero when it comes to pain.Patrick --- On Sun, 6/23/13, Susan Zimmerman <[email protected]> wrote:
From: Susan Zimmerman <[email protected]> Subject: Re: [CMLHope] BCR-ABL Results To: [email protected] Date: Sunday, June 23, 2013, 2:14 PM So Happy for you, SuzieQ! Not happy about the sciatica, etc., so hope you can conquer that soon. I am beginning tasigna on Wednesday at the lowest dose. I've been off all meds for 6 yrs and 3 mos., and can hardly move with like sludge in my veins. Absolutely no energy. The numbers were 17.7 for the recent fish test, so decided it was time. Please pray I tolerate this drug and have no more brain bleeds from the medication as I did with gleevec. My doc tells me 125 mg. once a day is the lowest dose. Can anyone verify this for me? I'm very concerned, as he had never heard of bosutinib two months ago, but now did not recommend it for me. Susan "Look among the nations and watch; be utterly astounded! For I will work a work in your days which you would not believe, though it were told you." Hab. 1:5 -----Original Message----- From: Suzieq <[email protected]> To: cmlhope <[email protected]> Sent: Sun, Jun 23, 2013 12:35 pm Subject: [CMLHope] BCR-ABL Results Hello everyone: I don't know if I posted my results or not, but they came back "none detected" once again........it's been this way straight through since the beginning of 2010......YIPPEE!!! My doctor is letting me cut the Gleevec back to 100mgs a day and we will see how that does. I will celebrate my tenth anniversary of my diagnosis next February 6th (according to my mom as that's her birthday and she always reminds me that I called her and told her on her birthday about the diagnosis.) I see the new Pain Management Specialist this coming Friday. I do hope he is able to help me. I have had two awful bad nights in a row now. Was doing much better up till then. Been seeing my Chiropractor regular and he's been helping me quite a bit with my Sciatic leg pain and hip pain. But, then the arthritis in the SI joints decided to act up and there isn't a whole lot he can do for that. I've been hitting my bottle of pain meds pretty regular for past two days. I am beginning to think my husband may be right about me being in a wheel chair soon. But, I will do all I can to fight that and keep going. I don't mind walking with my cane if I need to, but don't want to give into the wheel chair before I turn 60 years old. Alright, gotta get going now. Y'all have a great day and enjoy the summer..... Suzieq -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. For more options, visit https://groups.google.com/groups/opt_out. -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. For more options, visit https://groups.google.com/groups/opt_out. -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. For more options, visit https://groups.google.com/groups/opt_out.
