Those vacations can backfire. A few months ago, I was in really bad shape, 
undoubtedly caused by Tasigna.
I did not take Tasigna for ten days and then resumed the regular dose.
The next blood test, about two months later, showed that my log reduction 
had decreased from 3.4 to 2.5. Ouch!!!
The two tests three and six months after that, showed a 3.0 log reduction, 
which is where I am now.
Needless to say, I have been taking my meds religiously ever since.
There must be some secret which has not been unlocked yet. 
Why can some people get away with not taking any TKIs for years, while 
others are instantly punished after skipping a few doses?


On Thursday, August 1, 2013 9:04:09 PM UTC-4, Sylvia wrote:
>
> Hi everyone 
> I wrote about 2 months ago that after 12 yrs on Gleevec I was going to 
> take a break and go off for a while.  My dr wasn't too pleased and said i 
> needed to come back in a month for a PCR.  Well my results went from a 4.5 
> log reduction to a 2.8 log reduction.  That's a lot in 1 month.  So I am 
> back on Gleevec.  It's like welcoming back an old friend.  I am thankful 
> for Gleevec as many of my CML friends didn't live long enough to try it. 
> Blessings to all 
> Sylvia Guenther 
> Dx 6/98

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