Hi Jeanie. It was such along time ago when I started ponatinib, I can't remember whether I was tired. I do have a tendency to " drop off " from time to time. I just turned 80 in January, so that may be part of the problem. As my hemoglobin counts go down, I certainly feel it. I go tomorrow for my blood test, so I will see if I go back the drug. Cheers John
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