Just wanted to say that I take OTC pain killers and have tried prescription 
ones. I have a right side pain that won't go away and they can't find out what 
it is. Nothing seems to help the pain.   
They are doing a ct scan in Sept to see if they can find it but they have 
already done that with no luck.  Blessings 

My Motto: Faith and Pills
Jeanie 🐟🐟18,s 
Dx 1/2004. CML Leukemia
Started Gleevec 2/2004
Started Tasigna  9/2009
Started Sprycel 11/2009
Started Ponatinib January 2015
Dr Balducci Moffitt Cancer Center

> On Jul 24, 2015, at 12:14 PM, "'Icandoallttc' via CMLHope" 
> <[email protected]> wrote:
> 
> Hi Joyce. 
> It looks like your liver counts are 1-10% common to increase on that drug.  
> Read the information that comes with the meds.   Read the whole document 
> through. 
> They will stabilize as well as other side effects.  
> It seems I will go from one side effect to another as time passes. 
> Fight on.  Good luck. 
> 
> My Motto: Faith and Pills
> Jeanie 🐟🐟18,s 
> Dx 1/2004. CML Leukemia
> Started Gleevec 2/2004
> Started Tasigna  9/2009
> Started Sprycel 11/2009
> Started Ponatinib January 2015
> Dr Balducci Moffitt Cancer Center
> 
>> On Jul 23, 2015, at 11:43 PM, Joyce Mesnarich <[email protected]> wrote:
>> 
>> Jeanie,
>> Thanks for your interest and suggestion.  We have gone over all his other 
>> meds with doctors and nothing should affect the liver.  He doesn't take any 
>> OVC pain meds, or any pain meds.  And he does not drink alcohol.  The 
>> primary doctor says that the drug information for bosulif says it can cause 
>> liver problems, but Dr Talpaz is less certain of that and he is the 
>> specialist.  He says he is watching it closely and I guess we will just 
>> trust him.  Wayne is getting blood tests every other week locally and they 
>> are sent to Dr Talpaz.  The liver enzyme levels seem to have stabilized, 
>> although they are elevated.  As you say, faith and pills.  One of Wayne's 
>> mottos is "Better living through chemistry".  LOL  I think that used to be 
>> part of a TV ad for a large chemical company, maybe Du Pont or Monsanto.
>> 
>>               Joyce in IL
>> 
>> 
>>> On Jul 23, 2015, at 11:32 AM, 'Icandoallttc' via CMLHope wrote:
>>> 
>>> Be careful with his diet.  Ovc pain pills hurt the liver as well as other 
>>> drugs we take.  Ask your pharmacy if any other drugs he take are hurting 
>>> his liver.  It's hard but maybe they can figure out something. 
>>> Good luck. 
>>> 
>>> My Motto: Faith and Pills
>>> Jeanie 🐟🐟18,s 
>>> Dx 1/2004. CML Leukemia
>>> Started Gleevec 2/2004
>>> Started Tasigna  9/2009
>>> Started Sprycel 11/2009
>>> Started Ponatinib January 2015
>>> Dr Balducci Moffitt Cancer Center
>>> 
>>>> On Jul 22, 2015, at 2:01 PM, lrc lrc <[email protected]> wrote:
>>>> 
>>>> Joyce does he drink alcohol?
>>>> 
>>>>> On Jul 22, 2015 1:43 PM, "margood18 via CMLHope" 
>>>>> <[email protected]> wrote:
>>>>> Joyce, so glad to hear that your husband's PCR is lower and I hope that 
>>>>> his liver function will steady.  Best wishes to both of you.
>>>>> 
>>>>> Marcie
>>>>> 
>>>>> 
>>>>> -----Original Message-----
>>>>> From: Joyce Mesnarich <[email protected]>
>>>>> To: cmlhope <[email protected]>
>>>>> Sent: Wed, Jul 22, 2015 12:16 pm
>>>>> Subject: [CMLHope] New results
>>>>> 
>>>>> Hello everyone.  I have not had time to contribute for awhile.  But I 
>>>>> must let
>>>>> you all know the results of my husband's PCR at his last visit to Dr 
>>>>> Talpaz.  He
>>>>> was taken off Sprycel due to pleural effusion and we were hoping his
>>>>> undetectable would hold....but it did not.  He was subsequently put on 
>>>>> bosulif
>>>>> and not showing much improvement after 3 months.  So his dosage was 
>>>>> changed from
>>>>> 100 mg to 200 mg.  And now, after 3 more months, his PCR went from 8.7 to
>>>>> 0.127!!  Hopefully in another 3 months he will once again reach
>>>>> undetectable.
>>>>> 
>>>>> The downside of his test results is that the liver function
>>>>> tests have increased a lot.  The doctor will not really say that bosulif 
>>>>> is to
>>>>> blame, but nothing else has changed.  Has anyone of you CML warriors had 
>>>>> any
>>>>> problems with the liver while on TKI's?  Was there any treatment to help 
>>>>> the
>>>>> liver?
>>>>> 
>>>>> God bless you all.
>>>>> 
>>>>>             Joyce in IL
>>>>> 
>>>>> 
>>>>> -- 
>>>>> --
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