On Wednesday, June 17, 2015, David Bradley <[email protected]> wrote:
> Angelyn: I was in complete molecular remission. I stopped Gleevec in > December to commence another medication for my CLL. A PCR was done in > March and I was positive for CML. I went back on Gleevec (concurrently > administered with a reduced dose of my CLL med), and now, 3 months later, I > have a major molecular response. --David from Michigan > > > ------------------------------ > To: [email protected] > From: [email protected] > Subject: [CMLHope] Digest for [email protected] - 3 updates in 1 > topic > Date: Wed, 17 Jun 2015 10:21:09 +0000 > > [email protected] Google Groups > <https://groups.google.com/forum/?utm_source=digest&utm_medium=email/#%21overview> > <https://groups.google.com/forum/?utm_source=digest&utm_medium=email/#%21overview> > Topic digest > View all topics > > - Stopping Gleevec <#m_-2559529835317920018_group_thread_0> - 3 Updates > > Stopping Gleevec > <http://groups.google.com/group/cmlhope/t/4b2363f1837a8abd?utm_source=digest&utm_medium=email> > ANGELYN ESDERS <[email protected]>: Jun 17 01:02AM > > I just received an email from my oncologist telling me that it is safe for > me to stop Gleevec for 3 months.I started Gleevec in January 2001, and > reached cytogenic remission in July 2001. I've continued on 300mg per day.I > was in the study for 12 years.I feel like it is my safety net between > wellness and reoccurrence of CML.I am almost afraid to stop it. I no longer > have any side effects from it.Who has stopped Gleevec, and what have you > experienced as a result of doing so?Thanking you all for your input...Angie > in Canada > Giora Sharf <[email protected]>: Jun 17 09:35AM +0300 > > Hi Angie > > We have similar story. I started Glivec on 14.2.2001 and was on 400 mg > till 10.6.2014 when I agreed to my Dr's advise to stop. I am now 1 year > without treatment doing very well, monthly PCR are all in deep MR4.5 > response. > > I fully understand your concern, I had the same issues and didn’t agree to > stop for couple of years. When I saw the data indicating that all the > patients who stop and relapse (about 50-60 %) respond well when they > restart treatment, I agreed to stop. I also didn’t have severe side effects > on Glivec, but I am happy to be drug free and do very strict monthly or 6 > weeks monitoring. Please remember if you decide to stop- the most important > thing is a very strict monthly PCR on international scale. (IS) > > Good luck whatever you decide > > Giora > > > > From: [email protected] [mailto:[email protected]] On > Behalf Of ANGELYN ESDERS > Sent: Wednesday, June 17, 2015 4:03 AM > To: [email protected] > Subject: [CMLHope] Stopping Gleevec > > > > I just received an email from my oncologist telling me that it is safe for > me to stop Gleevec for 3 months. > > I started Gleevec in January 2001, and reached cytogenic remission in July > 2001. > > I've continued on 300mg per day. > > I was in the study for 12 years. > > I feel like it is my safety net between wellness and reoccurrence of CML. > > I am almost afraid to stop it. I no longer have any side effects from it. > > Who has stopped Gleevec, and what have you experienced as a result of > doing so? > > Thanking you all for your input... > > Angie in Canada > > -- > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to CMLHope-unsubscribe@ > googlegroups.com > For more options, visit this group at http://groups.google.com/ > group/CMLHope > --- > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > For more options, visit https://groups.google.com/d/optout. > ANGELYN ESDERS <[email protected]>: Jun 17 10:12AM > > Thank you for your kind letter, Giora. I remember you from years back. You > live in Tel Aviv? I am so happy to hear that you are doing so well. I feel > encouraged.Angie > From: Giora Sharf <[email protected]> > To: [email protected] > Sent: Wednesday, June 17, 2015 2:35 AM > Subject: RE: [CMLHope] Stopping Gleevec > > #yiv1061552755 #yiv1061552755 -- _filtered #yiv1061552755 {panose-1:2 4 5 > 3 5 4 6 3 2 4;} _filtered #yiv1061552755 {font-family:Calibri;panose-1:2 > 15 5 2 2 2 4 3 2 4;} _filtered #yiv1061552755 > {font-family:Tahoma;panose-1:2 11 6 4 3 5 4 4 2 4;} _filtered > #yiv1061552755 {font-family:Garamond;panose-1:2 2 4 4 3 3 1 1 8 > 3;}#yiv1061552755 #yiv1061552755 p.yiv1061552755MsoNormal, #yiv1061552755 > li.yiv1061552755MsoNormal, #yiv1061552755 div.yiv1061552755MsoNormal > {margin:0cm;margin-bottom:.0001pt;font-size:12.0pt;}#yiv1061552755 > a:link, #yiv1061552755 span.yiv1061552755MsoHyperlink > {color:blue;text-decoration:underline;}#yiv1061552755 a:visited, > #yiv1061552755 span.yiv1061552755MsoHyperlinkFollowed > {color:purple;text-decoration:underline;}#yiv1061552755 p > {margin-right:0cm;margin-left:0cm;font-size:12.0pt;}#yiv1061552755 > span.yiv1061552755EmailStyle18 {color:#1F497D;}#yiv1061552755 > .yiv1061552755MsoChpDefault {font-size:10.0pt;} _filtered #yiv1061552755 > {margin:72.0pt 90.0pt 72.0pt 90.0pt;}#yiv1061552755 > div.yiv1061552755WordSection1 {}#yiv1061552755 Hi AngieWe have similar > story. I started Glivec on 14.2.2001 and was on 400 mg till 10.6.2014 when > I agreed to my Dr's advise to stop. I am now 1 year without treatment doing > very well, monthly PCR are all in deep MR4.5 response.I fully understand > your concern, I had the same issues and didn’t agree to stop for couple of > years. When I saw the data indicating that all the patients who stop and > relapse (about 50-60 %) respond well when they restart treatment, I agreed > to stop. I also didn’t have severe side effects on Glivec, but I am happy > to be drug free and do very strict monthly or 6 weeks monitoring. Please > remember if you decide to stop- the most important thing is a very strict > monthly PCR on international scale. (IS)Good luck whatever you decideGiora > > From: [email protected] [mailto:[email protected]] On > Behalf Of ANGELYN ESDERS > Sent: Wednesday, June 17, 2015 4:03 AM > To: [email protected] > Subject: [CMLHope] Stopping Gleevec I just received an email from my > oncologist telling me that it is safe for me to stop Gleevec for 3 months.I > started Gleevec in January 2001, and reached cytogenic remission in July > 2001. I've continued on 300mg per day.I was in the study for 12 years.I > feel like it is my safety net between wellness and reoccurrence of CML.I am > almost afraid to stop it. I no longer have any side effects from it.Who has > stopped Gleevec, and what have you experienced as a result of doing > so?Thanking you all for your input...Angie in Canada-- > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to CMLHope-unsubscribe@ > googlegroups.com > For more options, visit this group at http://groups.google.com/ > group/CMLHope > --- > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > For more options, visit https://groups.google.com/d/optout.-- > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to CMLHope-unsubscribe@ > googlegroups.com > For more options, visit this group at http://groups.google.com/ > group/CMLHope > --- > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > For more options, visit https://groups.google.com/d/optout. > Back to top <#m_-2559529835317920018_digest_top> > You received this digest because you're subscribed to updates for this > group. You can change your settings on the group membership page. > To unsubscribe from this group and stop receiving emails from it send an > email to [email protected]. > > -- > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to CMLHope-unsubscribe@ > googlegroups.com > For more options, visit this group at http://groups.google.com/ > group/CMLHope > --- > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > For more options, visit https://groups.google.com/d/optout. > -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. For more options, visit https://groups.google.com/d/optout.
