Well after sending this off I finally hit on the right search terms and found 
this thread, 

https://www.mail-archive.com/[email protected]/msg03392.html

The "fix"  with the latest X11 update is still what Bill Scott said,

">> On 18 Feb 2014, at 22:49, William G. Scott <[email protected]> wrote:
>> 
>>> Hi Joe:
>>> 
>>> Thanks very much for your encouraging and kind words.
>>> 
>>> I just had a problem today that might be related.  Briefly, with 2 monitors 
>>> on 10.9.1, coot opens and then disappears .  I don’t get the “footprints”, 
>>> but that might be monitor or graphics-card specific.
>>> 
>>> In any case, the work-around (which I am not happy with) is to go into 
>>> System Preferences > Mission Control and uncheck the box that says 
>>> “Displays have separate Spaces”.  Then log out and log back in again, and 
>>> maybe it will work.
>>> 
>>> <Screen Shot 2014-02-18 at 2.43.47 PM.png>
>>> 
>>> If that fixes it, this is the bug.  No one wants to take responsibility:
>>> 
>>> https://xquartz.macosforge.org/trac/ticket/817
>>> 
>>> 
>>> HTH,
>>> 
>>> Bill"


Not a great solution but at least it works for now.

Cheers,
Len

Leonard M. Thomas Ph.D.
Macromolecular Crystallography Laboratory Manager
University of Oklahoma
Department of Chemistry and Biochemistry
Stephenson Life Sciences Research Center
101 Stephenson Parkway
Norman, OK 73019
405-325-1126
[email protected]
http://barlywine.chem.ou.edu
http://structuralbiology.ou.edu
________________________________________
From: Mailing list for users of COOT Crystallographic Software 
[[email protected]] on behalf of Paul Emsley [[email protected]]
Sent: Monday, June 02, 2014 10:33 AM
To: [email protected]
Subject: Re: No graphics window on osx 10.9

On 02/06/14 16:15, Thomas, Leonard M. wrote:
> Hello All,
>
> I just upgraded my Mac to 10.9.  I have tried both the stable version of coot 
> 0.7.1 and also a daily build of 0.8 and still have the same problem of no 
> graphics window showing up.   The terminal output ends at
>
> (set-display-lists-for-maps 0)
> load "tips-gui.scm"
> load "check-for-updates.scm"
> load "jligand-gui.scm"
> load "get-recent-pdbe.scm"
> load "extensions.scm"
> load "shelx-extensions.scm"
> (filter-fileselection-filenames-state)
> (get-active-map-drag-flag)
> (use-graphics-interface-state)
>
> Any ideas as to what I maybe missing are welcome.
>

Dear Len,

I understand that crystallography is tricky on 10.9.

At a guess, X11 has not been started before you try to run coot.  So
give that a go?  Maybe something to do with the version/distribution of
X11 you are running?

One day we will make a native (non-X11) version of Coot, so this problem
will go away.  But not today.

Paul.

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