>
> Does anyone know if Ray would be compatible with diginorm?
> http://arxiv.org/abs/1203.4802
> I ask because I'm not sure if the normalisation process outlined in the
> paper would mess with the determination of graph loops by Ray.
>
Titus's diginorm is very cool, but it currently has some caveats:
- it doesn't work with paired-end reads yet
- the normalization process throws away all repeat information
You may be better off just sub-sampling your read file. ie. if N reads, use
first N/4 of them.
--
--Torsten Seemann
--Victorian Bioinformatics Consortium, Dept. Microbiology, Monash
University, AUSTRALIA
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