With an array of Bloom filter I presume ? On 17/09/12 07:22 PM, Torsten Seemann wrote: > But N/4 reads will likely contain all the things that diginorms would > weed out, right ? > Does diginorm works with read paths in the de Bruijn stored in its Bloom > filter ? > If not, not only diginorm does not use pairs, but it does not use read > threading neither. > > > It does nothing that complicated. Just looks at kmer frequencies and throws > out reads that have k-mers we've already seen enough times. But it's > one-pass, fast, memory efficient algorithm. Not good for GENOME de novo > assembly at the moment, but very useful for de novo RNA-Seq as it flattens > the coverages of transcripts. > > -- > --Torsten Seemann > --Victorian Bioinformatics Consortium, Dept. Microbiology, Monash University, > AUSTRALIA >
------------------------------------------------------------------------------ Live Security Virtual Conference Exclusive live event will cover all the ways today's security and threat landscape has changed and how IT managers can respond. Discussions will include endpoint security, mobile security and the latest in malware threats. http://www.accelacomm.com/jaw/sfrnl04242012/114/50122263/ _______________________________________________ Denovoassembler-users mailing list Denovoassembler-users@lists.sourceforge.net https://lists.sourceforge.net/lists/listinfo/denovoassembler-users
