The $80 personal reader

[Greg Kearney]

Yes a blind person should be able to get this running by themselves.  
The only part which might require a sighted user is making Preview or  
Acrobat Reader the external application. But even if you didn't do  
this you could still use it; the default behavior of the program is  
to produce the PDF document and then open a Finder window to where  
the document was stored so you could just find it in that window and  
open it. The files are stored with increasing numbers and each day a  
new directory for that day's PDF is made.

Also the PDF will be searchable in Spotlight as well.
Greg Kearney