On Fri, Aug 7, 2020 at 2:46 PM John Clark <johnkcl...@gmail.com> wrote:
> On Fri, Aug 7, 2020 at 2:51 PM Jason Resch <jasonre...@gmail.com> wrote: > > > The scientific consensus is based on scientific studies, is it not? >> > > Yes. > > *> Every single study <https://c19study.com/> (dozens of them) that >> investigated early and prophylactic use of HCQ showed a benefit, without >> exception.* >> > > A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for > Covid-19 <https://www.nejm.org/doi/full/10.1056/NEJMoa2016638> > > *> So then, what is the scientific consensus on early/prophylactic use?* > > > *"CONCLUSIONS: After high-risk or moderate-risk exposure to Covid-19, > hydroxychloroquine did not prevent illness compatible with Covid-19 or > confirmed infection when used as postexposure prophylaxis within 4 days > after exposure. [...] Side effects were more common with hydroxychloroquine > than with placebo"* > > The *CONCLUSIONS* don't align with what the *RESULTS* section said right above. "We enrolled 821 asymptomatic participants. Overall, 87.6% of the participants (719 of 821) reported a high-risk exposure to a confirmed Covid-19 contact. The incidence of new illness compatible with Covid-19 did not differ significantly between participants receiving hydroxychloroquine (49 of 414 [11.8%]) and those receiving placebo (58 of 407 [14.3%]); the absolute difference was −2.4 percentage points (95% confidence interval, −7.0 to 2.2; P=0.35). Side effects were more common with hydroxychloroquine than with placebo (40.1% vs. 16.8%), but no serious adverse reactions were reported." So infection rates in the control group were 14.3% and in the group receiving HCQ were 11.8%. That's an absolute risk reduction of (14.3-11.8)/14.3 = 17.5%. Moreover, the claim is that HCQ reduces severity of the symptoms, leading to less hospitalization and death, not that it grants immunity from contracting it. The test did not find a negative result, it failed to reach statistical significance because their sample size was too small. See more information about that study here: https://c19study.com/boulware.html Jason -- You received this message because you are subscribed to the Google Groups "Everything List" group. To unsubscribe from this group and stop receiving emails from it, send an email to everything-list+unsubscr...@googlegroups.com. To view this discussion on the web visit https://groups.google.com/d/msgid/everything-list/CA%2BBCJUgZqodLXtJpG9AZsoAQQKEGoe1hSY97WAvufdTsD6b%2BUQ%40mail.gmail.com.
